Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | BRD2 | P25440 | 1/20 | 0.43 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.43 |
| ▸ | IDH1 | O75874 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.42 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
| ▸ | PRKCG | P05129 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | PRKCB | P05771 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26065256 | 0.92 | ALDH1A1 (0.48) | ALDH1A1MAPTPKMBRD4BRD2 | |
| SCHEMBL26065398 | 0.92 | ALDH1A1 (0.48) | ALDH1A1MAPTPKMBRD4BRD2 | |
| SCHEMBL26065566 | 0.85 | MAPT (0.47) | ALDH1A1MAPTPKMUSP2PDK1 | |
| SCHEMBL27070045 | 0.85 | KMT2A (0.47) | ALDH1A1PKMTRPV4KDM4EKMT2A | |
| SCHEMBL26064736 | 0.84 | TRPV4 (0.42) | ALDH1A1PKMTRPV4KDM4EKMT2A | |
| SCHEMBL30719568 | 0.82 | TRPV4 (0.46) | TRPV4KDM4E | |
| SCHEMBL30719550 | 0.82 | TRPV4 (0.46) | TRPV4KDM4E | |
| SCHEMBL27346556 | 0.82 | TRPV4 (0.46) | TRPV4KDM4E | |
| SCHEMBL26065980 | 0.82 | POLB (0.54) | ALDH1A1MAPTPKMTRPV4KDM4E | |
| SCHEMBL25369198 | 0.81 | TRPV4 (0.46) | TRPV4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023164063-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2023-08-31 | — | — | WO | disclosed |