Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.70 |
| ▸ | HPGD | P15428 | 4/20 | 0.70 |
| ▸ | POLB | P06746 | 2/20 | 0.70 |
| ▸ | TP53 | P04637 | 4/20 | 0.68 |
| ▸ | GAA | P10253 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | RAB9A | P51151 | 6/20 | 0.63 |
| ▸ | NPC1 | O15118 | 5/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.63 |
| ▸ | AHR | P35869 | 2/20 | 0.63 |
| ▸ | F10 | P00742 | 2/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31552888 | 0.82 | ALDH1A1 (0.80) | ALDH1A1KDM4EHPGDPOLBTP53 | |
| SCHEMBL15233665 | 0.82 | ALDH1A1 (0.80) | ALDH1A1KDM4EHPGDPOLBTP53 | |
| SCHEMBL24711273 | 0.81 | LMNA (0.86) | ALDH1A1KDM4EHPGDPOLBTP53 | |
| SCHEMBL28894148 | 0.81 | TP53 (1.00) | ALDH1A1KDM4EHPGDPOLBTP53 | |
| SCHEMBL26066041 | 0.81 | TP53 (0.63) | ALDH1A1KDM4EHPGDPOLBTP53 | |
| SCHEMBL14363235 | 0.81 | TP53 (0.81) | ALDH1A1KDM4EHPGDTP53GAA | |
| SCHEMBL7881086 | 0.81 | MAPT (0.72) | ALDH1A1KDM4EHPGDTP53GAA | |
| SCHEMBL6785591 | 0.81 | MAPK14 (0.74) | ALDH1A1KDM4ETP53GAAMAPT | |
| SCHEMBL27933848 | 0.81 | MEN1 (0.78) | ALDH1A1KDM4EHPGDTP53GAA | |
| SCHEMBL31680510 | 0.80 | SMN1; SMN2 (0.88) | ALDH1A1KDM4EHPGDPOLBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3628374-B1 | BCL-3 INHIBITORS | UNIV COLLEGE CARDIFF CONSULTANTS LTD (GB) | 2023-08-30 | — | — | EP | disclosed |