Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26065421 | 0.92 | HPGD (0.37) | HPGDPDE7AALDH1A1HTTNAMPT | |
| SCHEMBL25370098 | 0.85 | HPGD (0.32) | HPGDKDM2BACHEMEN1KMT2A | |
| SCHEMBL26065956 | 0.84 | HPGD (0.39) | HPGDPDE7AALDH1A1HTTNAMPT | |
| SCHEMBL26065442 | 0.82 | KDM4E (0.41) | HPGDPDE7AALDH1A1HTTNAMPT | |
| SCHEMBL26064882 | 0.81 | MEN1 (0.39) | HPGDPDE7AALDH1A1HTTNAMPT | |
| SCHEMBL26065959 | 0.81 | PDE7A (0.39) | HPGDPDE7AALDH1A1HTTNAMPT | |
| SCHEMBL26065952 | 0.81 | MEN1 (0.38) | HPGDPDE7AALDH1A1HTTNAMPT | |
| SCHEMBL27034396 | 0.80 | KDM2B (0.36) | HPGDKDM2BACHEALDH1A1MEN1 | |
| SCHEMBL26065653 | 0.78 | PDE7A (0.40) | HPGDPDE7AALDH1A1NAMPTMEN1 | |
| SCHEMBL25373015 | 0.77 | HPGD (0.31) | HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023164063-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2023-08-31 | — | — | WO | disclosed |