Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 4/20 | 0.36 |
| ▸ | DDR1 | Q08345 | 3/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.35 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26064882 | 0.92 | MEN1 (0.39) | MEN1KMT2AHPGDALDH1A1HTT | |
| SCHEMBL25372914 | 0.86 | HPGD (0.32) | MEN1KMT2AHPGD | |
| SCHEMBL26066151 | 0.85 | EBP (0.41) | — | |
| SCHEMBL27070068 | 0.83 | HPGD (0.46) | MEN1KMT2AHPGDALDH1A1NAMPT | |
| SCHEMBL26065421 | 0.82 | HPGD (0.37) | MEN1KMT2AHPGDALDH1A1HTT | |
| SCHEMBL26065956 | 0.81 | HPGD (0.39) | MEN1KMT2AHPGDALDH1A1HTT | |
| SCHEMBL27346368 | 0.81 | CTSK (0.39) | MEN1KMT2AHPGDALDH1A1DDR1 | |
| SCHEMBL27346508 | 0.81 | CTSK (0.39) | MEN1KMT2AHPGDALDH1A1DDR1 | |
| SCHEMBL26066065 | 0.81 | HPGD (0.38) | MEN1KMT2AHPGDALDH1A1HTT | |
| SCHEMBL26065442 | 0.80 | KDM4E (0.41) | MEN1KMT2AHPGDALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023164063-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2023-08-31 | — | — | WO | disclosed |