Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | BRD2 | P25440 | 1/20 | 0.37 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26065956 | 0.86 | HPGD (0.39) | KDM4EGAAALDH1A1HPGDPDE7A | |
| SCHEMBL25368145 | 0.85 | ALDH1A1 (0.33) | KDM4EGAAALDH1A1HPGDCYP2D6 | |
| SCHEMBL26066065 | 0.82 | HPGD (0.38) | KDM4EGAAALDH1A1HPGDPDE7A | |
| SCHEMBL26065421 | 0.81 | HPGD (0.37) | KDM4EGAAALDH1A1HPGDPDE7A | |
| SCHEMBL25365278 | 0.81 | BRD4 (0.35) | KDM4EALDH1A1HPGDBRD4BRD2 | |
| SCHEMBL26064882 | 0.81 | MEN1 (0.39) | KDM4EGAAALDH1A1HPGDPDE7A | |
| SCHEMBL26065959 | 0.81 | PDE7A (0.39) | KDM4EALDH1A1HPGDPDE7ANAMPT | |
| SCHEMBL26065952 | 0.80 | MEN1 (0.38) | KDM4EGAAALDH1A1HPGDPDE7A | |
| SCHEMBL27034424 | 0.79 | CHRM4 (0.35) | KDM4EALDH1A1HPGDBRD4BRD2 | |
| SCHEMBL26065964 | 0.75 | ALDH1A1 (0.46) | KDM4EGAAALDH1A1BRD4BRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023164063-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2023-08-31 | — | — | WO | disclosed |