SCHEMBL26067020

SCHEMBL26067020

COc1ccc(C(NCCCC[C@H](NC(=O)COCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCN)C(=O)NC2=CC=C(CO)CC2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.33

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ NPY1R P25929 4/20 0.33
▸ NPY4R P50391 2/20 0.33
▸ TLR2 O60603 1/20 0.33
▸ GLP1R P43220 7/20 0.32
▸ CCKAR P32238 1/20 0.32
▸ CCKBR P32239 1/20 0.32
▸ ADORA3 P0DMS8 1/20 0.32
▸ HDAC1 Q13547 1/20 0.31
▸ HDAC7 Q8WUI4 1/20 0.31
▸ CPA1 P15085 1/20 0.31
▸ CPA2 P48052 1/20 0.31
▸ CPA4 Q9UI42 1/20 0.31
▸ KIF11 P52732 1/20 0.30
▸ EPOR P19235 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26066857 0.87 HDAC8 (0.39) NPY1RNPY4RCCKARCCKBRHDAC1
SCHEMBL26066853 0.87 HDAC8 (0.39) NPY1RNPY4RCCKARCCKBRHDAC1
SCHEMBL25218460 0.85 HDAC8 (0.36) NPY1RNPY4RGLP1RCCKARCCKBR
SCHEMBL26066952 0.81 ALDH1A1 (0.39) ADORA3HDAC1HDAC7KIF11EPOR
SCHEMBL25242026 0.78 FOLH1 (0.37) HDAC1HDAC7
SCHEMBL25242024 0.78 FOLH1 (0.37) HDAC1HDAC7
SCHEMBL19732156 0.77 FOLH1 (0.37) HDAC1HDAC7
SCHEMBL25245450 0.76 FOLH1 (0.35) GLP1RHDAC1HDAC7
SCHEMBL27189832 0.75 HDAC8 (0.34) GLP1RHDAC1HDAC7
SCHEMBL27190126 0.75 HDAC8 (0.34) GLP1RHDAC1HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230270867-A1 CONJUGATE IN WHICH FL118 DRUG IS LINKED TO ACID-SENSITIVE LINKER, AND IMMUNOCONJUGATE USING SAME PINOTBIO, INC. (KR) 2023-08-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230270867-A1 CONJUGATE IN WHICH FL118 DRUG IS LINKED TO ACID-SENSITIVE LINKER, AND IMMUNOCONJUGATE USING SAME SLC46A1, SLC47A1, FOLR1 NPY1R 3532/4885NPY4R 4592/4885TLR2 3086/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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