SCHEMBL26067244

SCHEMBL26067244

N/C(=N\C(=N/Cc1cccc2oc3ccc(-c4cccc5ccccc45)cc3c12)c1ccccc1)c1ccc(-c2cccc3ccccc23)cc1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN1 Q05586 1/20 0.33
GRIN2B Q13224 1/20 0.33
HTR2B P41595 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
BACE1 P56817 2/20 0.33
IDO1 P14902 1/20 0.32
MAP1LC3B Q9GZQ8 1/20 0.32
MAP1LC3A Q9H492 1/20 0.32
F2 P00734 1/20 0.32
F10 P00742 1/20 0.32
PLG P00747 1/20 0.32
PLAU P00749 1/20 0.32
PLAT P00750 1/20 0.32
PRSS1 P07477 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
MCL1 Q07820 1/20 0.32
ACMSD Q8TDX5 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25651632 0.93 HTR2B (0.33) GRIN2BHTR2BIDO1
SCHEMBL24314978 0.91 BACE1 (0.33) GRIN2BHTR2BBACE1IDO1
SCHEMBL25652005 0.90 GRIN2B (0.35) GRIN2BHTR2BBACE1IDO1CHEK2
SCHEMBL23820565 0.90 HTR2B (0.31) HTR2BIDO1
SCHEMBL26067605 0.89 GRIN1 (0.33) GRIN1GRIN2BHTR2BBACE1
SCHEMBL25652287 0.88 GRIN2B (0.31) GRIN1GRIN2BHTR2BCYP1A2
SCHEMBL24658273 0.88 GRIN2B (0.39) GRIN1GRIN2BHTR2BIDO1PRSS1
SCHEMBL24315035 0.87 GRIN2B (0.39) GRIN1GRIN2BHTR2B
SCHEMBL25652155 0.87 ALOX5 (0.38) GRIN1GRIN2BHTR2BIDO1CHEK2
SCHEMBL24314408 0.86 GRIN2B (0.37) GRIN1GRIN2BHTR2BIDO1PRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4235829-A1 ORGANIC LIGHT-EMITTING DEVICE Lg Chem, Ltd. (KR) 2023-08-30 EP disclosed