Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.57 |
| ▸ | NPC1 | O15118 | 7/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2096075 | 0.94 | RAB9A (0.64) | RAB9ANPC1MAPTALDH1A1MEN1 | |
| SCHEMBL21962990 | 0.88 | RAB9A (0.57) | RAB9ANPC1MAPTALDH1A1MEN1 | |
| SCHEMBL3117692 | 0.83 | RAB9A (0.62) | RAB9ANPC1MAPTALDH1A1MEN1 | |
| SCHEMBL2447269 | 0.77 | RAB9A (0.52) | RAB9ANPC1MAPTALDH1A1MEN1 | |
| SCHEMBL914552 | 0.77 | RAB9A (0.68) | RAB9ANPC1MAPTALDH1A1MEN1 | |
| SCHEMBL13144514 | 0.77 | MAPT (0.70) | RAB9ANPC1MAPTALDH1A1MEN1 | |
| SCHEMBL22622703 | 0.77 | RAB9A (0.46) | RAB9ANPC1MAPTALDH1A1MEN1 | |
| SCHEMBL2445404 | 0.77 | RAB9A (0.55) | RAB9ANPC1MAPTALDH1A1MEN1 | |
| SCHEMBL2452993 | 0.77 | RAB9A (0.58) | RAB9ANPC1MAPTALDH1A1MEN1 | |
| SCHEMBL5804686 | 0.76 | SMN1; SMN2 (0.48) | RAB9ANPC1MAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163776-B2 | Immunomodulation by administering thione-forming dithiobis-heterocyclic compound, increased natural killer cell activity, expansion of NK cell population, decreased B cell population, decreased antibody production | GRASSETTI FAMILY TRUST (US) | 2012-04-24 | — | — | US | disclosed |