SCHEMBL5804686

SCHEMBL5804686

Cc1csc(SSc2nc(C)cs2)n1

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 5/20 0.48
NOS1 P29475 1/20 0.48
ALDH1A1 P00352 1/20 0.41
LMNA P02545 1/20 0.41
RAB9A P51151 5/20 0.40
GAA P10253 4/20 0.40
NPC1 O15118 3/20 0.40
POLB P06746 2/20 0.40
HPGD P15428 3/20 0.38
MAPT P10636 1/20 0.38
KMT2A Q03164 3/20 0.37
MEN1 O00255 2/20 0.37
NPSR1 Q6W5P4 1/20 0.37
THRB P10828 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.36
USP2 O75604 1/20 0.36
TP53 P04637 1/20 0.36
HSD17B10 Q99714 1/20 0.36
MAPK1 P28482 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11836753 0.84 RAB9A (0.42) SMN1; SMN2NOS1ALDH1A1LMNARAB9A
SCHEMBL903172 0.82
SCHEMBL9334440 0.80
SCHEMBL15948524 0.77
SCHEMBL2606735 0.76 RAB9A (0.57) SMN1; SMN2ALDH1A1LMNARAB9AGAA
SCHEMBL11116642 0.75
SCHEMBL14619867 0.73 ALDH1A1 (0.49) ALDH1A1LMNARAB9AGAANPC1
SCHEMBL16137346 0.73 RAB9A (0.51) SMN1; SMN2ALDH1A1LMNARAB9AGAA
SCHEMBL11875330 0.73 ALDH1A1 (0.42) SMN1; SMN2ALDH1A1LMNARAB9AGAA
SCHEMBL11445458 0.72 SMN1; SMN2 (0.40) SMN1; SMN2NOS1ALDH1A1LMNARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116041812-B Vulcanized neoprene capable of being repeatedly processed and preparation method thereof 安徽忠德输送工程技术有限公司 2026-05-19 CN disclosed
CN-116041812-A Vulcanized neoprene capable of being repeatedly processed and preparation method thereof 安徽忠德输送工程技术有限公司 2023-05-02 CN disclosed
WO-2006085815-A1 THIAZOLE DERIVATIVES, THEIR PROCESS FOR THEIR PREPARATION AND THEIR USE IN THERAPY ASTRAZENECA AB (SE) 2006-08-17 WO disclosed
WO-2006075955-A1 PYRAZOLYL ACYLSULFONAMIDE DERIVATIVES AS ENDOTHELIN CONVERTING ENZYME INHIBITORS AND USEFUL IN THE TREATMENT OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE ASTRAZENECA AB (SE) 2006-07-20 WO disclosed
US-6943268-B2 Method for induction of L-selectin shedding SCIENCE & TECHNOLOGY CORPORATION @ UNM (US) 2005-09-13 US disclosed
US-20030092763-A1 Method for induction of L-selectin shedding SCIENCE & TECHNOLOGY CORPORATION @UNM 2003-05-15 US disclosed
US-6498189-B1 SUPPRESSION OF INFLAMMATION AND OF LYMPH NODE ENTRY BY CALMODULIN ANTAGONISTS; CELL ASSOCIATED PROTEIN DISULFIDE ISOMERASE INHIBITORS; P-AMINOPHENYLARSINE OXIDES UNIVERSITY OF NEW MEXICO 2002-12-24 US disclosed
US-6191297-B1 HYDROSILATION OF FUNCTIONALLIZED ALLYL COMPOUNDS, E.G. ALLYL CHLORIDE, BY HYDROGEN SILANES, E.G. DICHLOROMETHYLSILANE, USING A CATALYST OF A COMPLEX OF PLATINUM AND ONE OR MORE SULFUR-CONTAINING LIGANDS; EFFICIENCY DEGUSSA-HULS AG (DE) 2001-02-20 US disclosed
EP-0963993-A2 Process for preparing silanes with functional group at carbon-3 Degussa-Hüls Aktiengesellschaft (DE) 1999-12-15 EP disclosed
EP-0439585-B1 IMMOBILISATION OF LIGANDS BY RADIO-DERIVATIZED POLYMERS MAG GEORG MAYRHOFER & CO OHG (AT) 1997-10-29 EP disclosed
US-5196478-A Polystyrene, assays EPIPHARM ALLERGIE-SERVICE GESELLSCHAFT M.B.H. (AT) 1993-03-23 US disclosed
EP-0439585-A1 IMMOBILISATION OF LIGANDS BY RADIO-DERIVATIZED POLYMERS. EPIPHARM ALLERGIE SERVICE (AT) 1991-08-07 EP disclosed
WO-1991002768-A1 IMMOBILISATION OF LIGANDS BY RADIO-DERIVATIZED POLYMERS EPIPHARM ALLERGIE-SERVICE GESELLSCHAFT M.B.H. (AT) 1991-03-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030092763-A1 Method for induction of L-selectin shedding PDIA5, PDIA4, PDIA6 SMN1; SMN2 4805/4885NOS1 1049/4885ALDH1A1 1261/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.