Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22327377 | 1.00 | MAOB (0.35) | MAOBALDH1A1SMN1; SMN2KMT2APSMB8 | |
| SCHEMBL26068349 | 1.00 | MAOB (0.35) | MAOBALDH1A1SMN1; SMN2KMT2APSMB8 | |
| SCHEMBL25753981 | 0.94 | MAPT (0.38) | MAOBALDH1A1SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL22327417 | 0.93 | KDM4E (0.36) | MAOBALDH1A1SMN1; SMN2KMT2APSMB8 | |
| SCHEMBL22327218 | 0.93 | ALDH1A1 (0.35) | MAOBALDH1A1SMN1; SMN2KMT2APSMB8 | |
| SCHEMBL22598488 | 0.93 | ALDH1A1 (0.35) | MAOBALDH1A1SMN1; SMN2KMT2APSMB8 | |
| SCHEMBL22598389 | 0.93 | ALDH1A1 (0.35) | MAOBALDH1A1SMN1; SMN2KMT2APSMB8 | |
| SCHEMBL22598379 | 0.92 | MAOB (0.35) | MAOBALDH1A1SMN1; SMN2KMT2APSMB8 | |
| SCHEMBL22598234 | 0.92 | MAOB (0.35) | MAOBALDH1A1SMN1; SMN2KMT2APSMB8 | |
| SCHEMBL22598406 | 0.92 | MAOB (0.35) | MAOBALDH1A1SMN1; SMN2KMT2APSMB8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230257414-A1 | NUCLEOTIDE ANALOGUES | FIRST-CITIZENS BANK & TRUST COMPANY | 2023-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257414-A1 | NUCLEOTIDE ANALOGUES | ITPA, POLB, NUDT1 | MAOB 1827/4885ALDH1A1 1313/4885SMN1; SMN2 1787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.