Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | SYK | P43405 | 2/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 2/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.33 |
| ▸ | ABAT | P80404 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18003590 | 0.92 | PDE10A (0.41) | PTGS2SYKAKR1C3AKR1C2ALDH1A3 | |
| SCHEMBL16399585 | 0.82 | PDE10A (0.41) | PTGS2SYKAKR1C3AKR1C2ALDH1A3 | |
| SCHEMBL18003592 | 0.76 | ALDH1A1 (0.50) | ALDH1A1MAPTPDE10AHPGDTDP1 | |
| SCHEMBL30798672 | 0.72 | ALDH1A1 (0.40) | ALDH1A3ALDH1A1MAPTPOLBKCNH2 | |
| SCHEMBL932830 | 0.72 | ALDH1A1 (0.40) | ALDH1A3ALDH1A1MAPTPOLBKCNH2 | |
| SCHEMBL18003899 | 0.70 | SYK (0.45) | PTGS2SYKPDE10AMAP4K4PIK3CA | |
| SCHEMBL18003244 | 0.70 | PIK3CA (0.41) | PTGS2SYKALDH1A1MAPTPDE10A | |
| SCHEMBL18003894 | 0.69 | ALDH1A1 (0.47) | ALDH1A1MAPTPDE10AHPGDTDP1 | |
| SCHEMBL18003239 | 0.69 | SYK (0.40) | PTGS2SYKALDH1A3PDE10AMAP4K4 | |
| SCHEMBL1713698 | 0.67 | ALDH1A1 (0.57) | AKR1C3ALDH1A3ALDH1A1MAPTTRIM24 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219477-A1 | CYANOTRIAZOLE COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2023-08-02 | — | — | EP | disclosed |