Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | USP7 | Q93009 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18004446 | 0.91 | ESRRA (0.35) | TRPA1SCN5ASCN9AUSP7 | |
| SCHEMBL18004292 | 0.90 | IDO1 (0.39) | IDO1FFAR1AKT1HDAC1HDAC6 | |
| SCHEMBL18004306 | 0.89 | IDO1 (0.38) | IDO1FFAR1AKT1HDAC1HDAC6 | |
| SCHEMBL16399554 | 0.89 | SRD5A2 (0.39) | TRPA1SCN5ASCN9AUSP7 | |
| SCHEMBL18004308 | 0.86 | IDO1 (0.39) | IDO1FFAR1AKT1HDAC1HDAC6 | |
| SCHEMBL18004214 | 0.86 | MAOB (0.38) | TRPA1SCN5ASCN9A | |
| SCHEMBL18004399 | 0.83 | ESRRA (0.35) | IDO1 | |
| SCHEMBL18004211 | 0.83 | ESRRA (0.36) | — | |
| SCHEMBL18004092 | 0.83 | IDO1 (0.40) | IDO1TRPA1AKT1 | |
| SCHEMBL18004167 | 0.83 | TRPA1 (0.35) | IDO1TRPA1SCN5ASCN9AUSP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219477-A1 | CYANOTRIAZOLE COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2023-08-02 | — | — | EP | disclosed |