SCHEMBL16399554

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18004446	0.93	ESRRA (0.35)	SRD5A2SRD5A1TRPA1SCN5ASCN9A
	SCHEMBL16399270	0.91	SRD5A2 (0.41)	SRD5A2SRD5A1NR1H2QPCTPIEZO1
	SCHEMBL16398931	0.90	SRD5A2 (0.39)	SRD5A2SRD5A1NR1H2QPCTNR1H3
	SCHEMBL18004471	0.89	SRD5A2 (0.40)	SRD5A2SRD5A1NR1H2QPCTPIEZO1
	SCHEMBL18004226	0.89	SRD5A2 (0.38)	SRD5A2SRD5A1NR1H2QPCT
	SCHEMBL18004327	0.89	NR1H2 (0.40)	SRD5A2SRD5A1NR1H2QPCTNR1H3
	SCHEMBL18004440	0.89	SRD5A2 (0.39)	SRD5A2SRD5A1NR1H2QPCTPIEZO1
	SCHEMBL18004217	0.89	SRD5A2 (0.39)	SRD5A2SRD5A1NR1H2QPCTPIEZO1
	SCHEMBL26070342	0.89	IDO1 (0.38)	TRPA1SCN5ASCN9AUSP7
	SCHEMBL18004225	0.88	KDM1A (0.40)	SRD5A2SRD5A1TRPA1NR1H2QPCT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.