SCHEMBL26070568

SCHEMBL26070568

Nc1[nH]nnc1-c1cc(OCc2ccccc2)cc(OCc2ccccc2)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
MAOB P27338 4/20 0.44
MAPT P10636 3/20 0.44
GAA P10253 2/20 0.44
MAOA P21397 1/20 0.44
RAB9A P51151 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
MGAM O43451 1/20 0.44
SI P14410 1/20 0.44
MGAM2 Q2M2H8 1/20 0.44
IKBKE Q14164 1/20 0.43
PIK3CD O00329 1/20 0.43
PIK3CA P42336 1/20 0.43
PIK3CB P42338 1/20 0.43
PIK3CG P48736 1/20 0.43
PRKDC P78527 1/20 0.43
XDH P47989 1/20 0.42
GSTP1 P09211 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18005945 0.81 MEN1 (0.48) MEN1KMT2AMAOBMAPTRAB9A
SCHEMBL18004314 0.76 MAOB (0.47) MEN1KMT2AMAOBMAPTNPSR1
SCHEMBL26070984 0.76 IGF1R (0.42) MEN1KMT2AMAOBMAPTPIK3CD
SCHEMBL26071088 0.75 ADORA2A (0.42) MEN1KMT2AMAOBL3MBTL1PIK3CD
Hydrochloric Acid SCHEMBL4855249 0.75 IKBKE (0.46) MEN1KMT2AMAOBMAPTGAA
SCHEMBL26070912 0.74 IGF1R (0.45) MEN1KMT2AMAOBMAPTPIK3CD
SCHEMBL26071035 0.74 CYP4F2 (0.46) MAOBMAOA
SCHEMBL18004168 0.74 MEN1 (0.40) MEN1KMT2AMAOBNSD2AS3MT
SCHEMBL26071081 0.74 CYSLTR2 (0.41) PIK3CDPIK3CAPIK3CBPIK3CGPRKDC
SCHEMBL18004180 0.74 MEN1 (0.40) MEN1KMT2AMAOBGSTP1NSD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4219477-A1 CYANOTRIAZOLE COMPOUNDS Otsuka Pharmaceutical Co., Ltd. (JP) 2023-08-02 EP disclosed