Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | IGF1R | P08069 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | TTK | P33981 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18006438 | 0.86 | CYP11B1 (0.43) | ADORA2AADORA1IGF1RL3MBTL1KMT2A | |
| SCHEMBL26070568 | 0.75 | MEN1 (0.47) | IGF1RL3MBTL1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL26071081 | 0.75 | CYSLTR2 (0.41) | IGF1RPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL26071092 | 0.75 | IGF1R (0.39) | IGF1RPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL26070965 | 0.74 | IGF1R (0.42) | IGF1RPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL26070912 | 0.74 | IGF1R (0.45) | IGF1RPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL26071035 | 0.74 | CYP4F2 (0.46) | MAOB | |
| SCHEMBL26070984 | 0.73 | IGF1R (0.42) | IGF1RPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL18618063 | 0.71 | MPO (0.52) | KMT2AMEN1ALDH1A1MPOHPGD | |
| SCHEMBL26071079 | 0.71 | IGF1R (0.35) | IGF1RL3MBTL1PIK3CDPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219477-A1 | CYANOTRIAZOLE COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2023-08-02 | — | — | EP | disclosed |