Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18006408 | 0.89 | CYP4F2 (0.47) | CYP4F2CYP4A11GABRG2GABRB3GABRA5 | |
| SCHEMBL7451938 | 0.79 | GABRG2 (0.56) | CYP4F2CYP4A11GABRG2GABRB3GABRA5 | |
| SCHEMBL18006432 | 0.78 | CYP11B1 (0.51) | CYP4F2CYP4A11GABRG2GABRB3GABRA5 | |
| SCHEMBL18004687 | 0.78 | NR4A2 (0.45) | CYP4F2CYP4A11GABRG2GABRB3GABRA5 | |
| SCHEMBL18005947 | 0.78 | NAAA (0.47) | GABRG2GABRB3GABRA5GABRA3CYP11B1 | |
| SCHEMBL26070980 | 0.78 | NOS1 (0.48) | MAOBMAOA | |
| SCHEMBL26070984 | 0.77 | IGF1R (0.42) | MAOB | |
| SCHEMBL18004433 | 0.76 | NR4A2 (0.47) | CYP11B1MAOBMAOACYP11B2GRM5 | |
| SCHEMBL26071092 | 0.76 | IGF1R (0.39) | CYP11B1MAOBGRM5 | |
| SCHEMBL26071045 | 0.76 | MRGPRX4 (0.45) | MAOBMAOAMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219477-A1 | CYANOTRIAZOLE COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2023-08-02 | — | — | EP | disclosed |