Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SREBF2 | Q12772 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 7/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | ECE1 | P42892 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18005982 | 0.79 | KMT2A (0.47) | SREBF2KMT2AMEN1L3MBTL1APOBEC3G | |
| SCHEMBL26070602 | 0.78 | ALDH1A1 (0.54) | KMT2AMEN1L3MBTL1KDM4EMAPT | |
| SCHEMBL18005984 | 0.77 | RAB9A (0.46) | SREBF2KMT2AMEN1L3MBTL1APOBEC3G | |
| SCHEMBL2387037 | 0.75 | AKT2 (0.44) | KMT2AL3MBTL1KDM4EMAPTALDH1A1 | |
| SCHEMBL2781370 | 0.73 | KDM4E (0.85) | SREBF2KMT2AMEN1KDM4EAR | |
| SCHEMBL11213828 | 0.71 | SREBF2 (0.82) | SREBF2KMT2AMEN1KDM4EAR | |
| SCHEMBL11212983 | 0.71 | SREBF2 (0.82) | SREBF2KMT2AMEN1KDM4EAR | |
| SCHEMBL11215130 | 0.71 | SREBF2 (0.82) | SREBF2KMT2AMEN1KDM4EAR | |
| SCHEMBL18005019 | 0.71 | RAB9A (0.49) | SREBF2KMT2AMEN1L3MBTL1KDM4E | |
| SCHEMBL14081497 | 0.71 | SREBF2 (1.00) | SREBF2KMT2AMEN1KDM4EAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219477-A1 | CYANOTRIAZOLE COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2023-08-02 | — | — | EP | disclosed |