Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 2/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26071006 | 0.86 | CYP2D6 (0.42) | IGF1RLRRK2BACE1NOS3NOS1 | |
| SCHEMBL18006383 | 0.85 | KDM1A (0.43) | IGF1RLRRK2EP300KDM1ANR1H4 | |
| SCHEMBL18003506 | 0.79 | LRRK2 (0.43) | IGF1RLRRK2EP300KDM1ANR1H4 | |
| SCHEMBL26070907 | 0.77 | NFE2L2 (0.47) | IGF1R | |
| SCHEMBL26070898 | 0.76 | BTK (0.49) | — | |
| SCHEMBL18003498 | 0.74 | IGF1R (0.46) | IGF1RLRRK2KDM1A | |
| SCHEMBL26070953 | 0.73 | IGF1R (0.47) | IGF1RFFAR4 | |
| SCHEMBL26070997 | 0.73 | KDM4E (0.40) | IGF1R | |
| SCHEMBL26070900 | 0.73 | GAA (0.37) | — | |
| SCHEMBL18734457 | 0.73 | NR1H4 (0.45) | LRRK2BACE1NR1H4FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219477-A1 | CYANOTRIAZOLE COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2023-08-02 | — | — | EP | disclosed |