Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 5/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.38 |
| ▸ | YES1 | P07947 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.38 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18006326 | 0.84 | NFE2L2 (0.40) | NFE2L2MCHR1IGF1RADORA2ATGFBR1 | |
| SCHEMBL26070993 | 0.77 | IGF1R (0.44) | IGF1R | |
| SCHEMBL26071006 | 0.77 | CYP2D6 (0.42) | IGF1R | |
| SCHEMBL26071070 | 0.77 | SMN1; SMN2 (0.45) | KDM4E | |
| SCHEMBL26070953 | 0.76 | IGF1R (0.47) | IGF1R | |
| SCHEMBL26070997 | 0.75 | KDM4E (0.40) | IGF1REPHB4KDM4E | |
| SCHEMBL26070995 | 0.74 | KDM4E (0.42) | IGF1RKDM4E | |
| SCHEMBL18003498 | 0.74 | IGF1R (0.46) | IGF1RADORA2A | |
| SCHEMBL26070898 | 0.73 | BTK (0.49) | KDM4E | |
| SCHEMBL26070951 | 0.73 | SIRT2 (0.42) | IGF1RKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219477-A1 | CYANOTRIAZOLE COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2023-08-02 | — | — | EP | disclosed |