Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | IGF1R | P08069 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.34 |
| ▸ | PRKDC | P78527 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | NMT1 | P30419 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18006437 | 0.85 | CHEK1 (0.39) | SLC22A12CYP4F2CYP4A11KDM4EMAPT | |
| SCHEMBL26071018 | 0.83 | NOTUM (0.38) | SLC22A12NOTUMKDM4ESMN1; SMN2MAPT | |
| SCHEMBL26071043 | 0.79 | CHEK1 (0.43) | SLC22A12NOTUMSMN1; SMN2MAPTIGF1R | |
| SCHEMBL26070911 | 0.78 | CYP2C9 (0.47) | TSHRMEN1KMT2A | |
| SCHEMBL26071075 | 0.77 | CYSLTR2 (0.36) | SLC22A12NOTUMKDM4ESMN1; SMN2MAPT | |
| SCHEMBL26071012 | 0.77 | HSD17B10 (0.38) | SLC22A12NOTUMKDM4EMAPTALDH1A1 | |
| SCHEMBL26071092 | 0.76 | IGF1R (0.39) | SLC22A12NOTUMKDM4EMAPTALDH1A1 | |
| SCHEMBL26071016 | 0.76 | SLC22A12 (0.38) | SLC22A12NOTUMKDM4ESMN1; SMN2MAPT | |
| SCHEMBL26070898 | 0.75 | BTK (0.49) | SLC22A12NOTUMKDM4ESMN1; SMN2MAPT | |
| SCHEMBL26071014 | 0.75 | FFAR1 (0.38) | SLC22A12NOTUMKDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219477-A1 | CYANOTRIAZOLE COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2023-08-02 | — | — | EP | disclosed |