Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 2/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 2/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26070976 | 0.87 | PTGS2 (0.41) | FFAR1IGF1RCYSLTR2CYSLTR1GABRA1 | |
| SCHEMBL18006398 | 0.85 | CYP11B1 (0.37) | FFAR1SLC22A12CYSLTR2CYSLTR1GABRA1 | |
| SCHEMBL26071059 | 0.83 | PFKFB3 (0.39) | FFAR1SLC22A12IGF1RCYSLTR2CYSLTR1 | |
| SCHEMBL26071016 | 0.79 | SLC22A12 (0.38) | FFAR1SLC22A12CYSLTR2CYSLTR1MAPT | |
| SCHEMBL26070973 | 0.79 | GABRA1 (0.41) | FFAR1SLC22A12IGF1RGABRA1GABRG2 | |
| SCHEMBL26071043 | 0.78 | CHEK1 (0.43) | SLC22A12IGF1RCYSLTR2CYSLTR1MAPT | |
| SCHEMBL26070967 | 0.78 | CNR1 (0.36) | SLC22A12IGF1RCYSLTR2CYSLTR1GABRA1 | |
| SCHEMBL26071055 | 0.78 | ADORA2A (0.38) | SLC22A12IGF1RCYSLTR2CYSLTR1GABRA1 | |
| SCHEMBL26070961 | 0.77 | MEN1 (0.42) | SLC22A12IGF1RGABRA1GABRG2GABRB3 | |
| SCHEMBL26071075 | 0.76 | CYSLTR2 (0.36) | SLC22A12IGF1RCYSLTR2CYSLTR1GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219477-A1 | CYANOTRIAZOLE COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2023-08-02 | — | — | EP | disclosed |