Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2607288 | 1.00 | PRKDC (0.33) | PRKDCDPP4KDM4EALDH1A1GAA | |
| SCHEMBL2607283 | 1.00 | PRKDC (0.33) | PRKDCDPP4KDM4EALDH1A1GAA | |
| SCHEMBL2607511 | 1.00 | PRKDC (0.33) | PRKDCDPP4KDM4EALDH1A1GAA | |
| SCHEMBL2607223 | 0.97 | PRKDC (0.35) | PRKDCKDM4EALDH1A1GAATHRB | |
| SCHEMBL13146685 | 0.97 | PRKDC (0.35) | PRKDCKDM4EALDH1A1GAATHRB | |
| SCHEMBL2607287 | 0.94 | DPP4 (0.32) | PRKDCDPP4KDM4EALDH1A1GAA | |
| SCHEMBL2607337 | 0.94 | DPP4 (0.32) | PRKDCDPP4KDM4EALDH1A1GAA | |
| SCHEMBL2607154 | 0.93 | PRKDC (0.33) | PRKDCKDM4EALDH1A1GAATHRB | |
| SCHEMBL16522153 | 0.93 | DPP4 (0.31) | PRKDCDPP4KDM4EALDH1A1GAA | |
| SCHEMBL2607453 | 0.92 | KDM4E (0.38) | PRKDCDPP4KDM4EALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120095236-A1 | PYRROLOPYRROLE DERIVATIVES, THEIR MANUFACTURE AND USE AS SEMICONDUCTORS | BASF SE (DE) | 2012-04-19 | — | — | US | disclosed |
| US-20120095236-A1 | PYRROLOPYRROLE DERIVATIVES, THEIR MANUFACTURE AND USE AS SEMICONDUCTORS | BASF SE (DE) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095236-A1 | PYRROLOPYRROLE DERIVATIVES, THEIR MANUFACTURE AND USE AS SEMICONDUCTORS | PPOX, PIN1, DDT | PRKDC 173/4885DPP4 2747/4885KDM4E 2052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.