Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 18/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29395846 | 1.00 | PTGS2 (0.41) | PTGS2PTGS1HSD11B1IDO1 | |
| SCHEMBL26072918 | 0.88 | PTGS2 (0.42) | PTGS2PTGS1HSD11B1IDO1 | |
| SCHEMBL26072738 | 0.84 | KCNH2 (0.34) | PTGS2 | |
| SCHEMBL26072702 | 0.84 | PTGS2 (0.40) | PTGS2PTGS1HSD11B1IDO1 | |
| SCHEMBL26072089 | 0.83 | PTGS2 (0.40) | PTGS2PTGS1IDO1 | |
| SCHEMBL26072059 | 0.83 | KDM5A (0.39) | PTGS2PTGS1HSD11B1IDO1 | |
| SCHEMBL26072604 | 0.83 | PTGS2 (0.39) | PTGS2PTGS1HSD11B1IDO1 | |
| SCHEMBL26072721 | 0.82 | PTGS2 (0.47) | PTGS2PTGS1IDO1 | |
| SCHEMBL26072708 | 0.82 | PTGS2 (0.38) | PTGS2PTGS1HSD11B1IDO1 | |
| SCHEMBL26072322 | 0.81 | KDM4E (0.41) | PTGS2PTGS1HSD11B1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230312565-A1 | 1H-PYRROLO[3,2-C]PYRIDINE AND 1H-PYRROLO[2,3-C]PYRIDINE DERIVATIVES AS TLR9 INHIBITORS FOR THE TREATMENT OF FIBROSIS | BRISTOL MYERS SQUIBB CO (US) | 2023-10-05 | — | — | US | disclosed |
| US-20230312565-A1 | 1H-PYRROLO[3,2-C]PYRIDINE AND 1H-PYRROLO[2,3-C]PYRIDINE DERIVATIVES AS TLR9 INHIBITORS FOR THE TREATMENT OF FIBROSIS | BRISTOL MYERS SQUIBB CO (US) | 2023-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230312565-A1 | 1H-PYRROLO[3,2-C]PYRIDINE AND 1H-PYRROLO[2,3-C]PYRIDINE DERIVATIVES AS TLR9 INHIBITORS FOR THE TREATMENT OF FIBROSIS | TLR9, TLR1, TLR7 | PTGS2 1061/4885PTGS1 356/4885HSD11B1 3646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.