⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL482456 | 0.97 | TRIM24 (0.53) | — | |
| SCHEMBL759705 | 0.94 | — | — | |
| SCHEMBL806913 | 0.81 | — | — | |
| SCHEMBL6244784 | 0.79 | TRIM24 (0.69) | — | |
| SCHEMBL6243997 | 0.79 | TRIM24 (0.69) | — | |
| SCHEMBL7064998 | 0.79 | TRIM24 (0.69) | — | |
| Ethylene SCHEMBL7384690 | 0.78 | TRIM24 (0.60) | — | |
| SCHEMBL696582 | 0.77 | — | — | |
| SCHEMBL2047984 | 0.74 | TRIM24 (0.71) | — | |
| SCHEMBL11407439 | 0.74 | TRIM24 (0.71) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4249071-A2 | BENZOAZEPINE ANALOGS AS INHIBITING AGENTS FOR BRUTON'S TYROSINE KINASE | Biogen MA Inc. (US) | 2023-09-27 | — | — | EP | disclosed |