Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 8/20 | 0.66 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26649544 | 0.86 | PLA2G2A (0.65) | DHODHPLA2G2AMEN1KMT2AALDH1A1 | |
| SCHEMBL26074081 | 0.84 | DHODH (0.65) | DHODHPLA2G2AMEN1KMT2AMCL1 | |
| SCHEMBL23590206 | 0.84 | KDM4E (0.50) | DHODHPLA2G2AMEN1KMT2AERN1 | |
| SCHEMBL26075554 | 0.84 | DHODH (0.51) | DHODHPLA2G2AMEN1KMT2AALDH1A1 | |
| SCHEMBL29617662 | 0.81 | DHODH (0.97) | DHODHPLA2G2AMEN1KMT2AALDH1A1 | |
| SCHEMBL23590248 | 0.81 | DHODH (0.97) | DHODHPLA2G2AMEN1KMT2AALDH1A1 | |
| SCHEMBL27939580 | 0.81 | CYP19A1 (0.56) | DHODHMEN1KMT2AMAPT | |
| SCHEMBL26649316 | 0.80 | DHODH (0.53) | DHODHMEN1KMT2AALDH1A1GAA | |
| SCHEMBL16742008 | 0.80 | DHODH (1.00) | DHODHPLA2G2AMEN1KMT2AALDH1A1 | |
| SCHEMBL26075569 | 0.80 | DHODH (0.48) | DHODHPLA2G2AMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230303710-A1 | METHODS AND COMPOSITIONS FOR INHIBITION OF DIHYDROOROTATE DEHYDROGENASE IN COMBINATION WITH AN ANTI-CD38 THERAPEUTIC AGENT | OHIO STATE INNOVATION FOUNDATION (US) | 2023-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230303710-A1 | METHODS AND COMPOSITIONS FOR INHIBITION OF DIHYDROOROTATE DEHYDROGENASE IN COMBINATION WITH AN ANTI-CD38 THERAPEUTIC AGENT | DHODH, CD38, DPYD | DHODH 1/4885PLA2G2A 1679/4885MEN1 2373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.