Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 6/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | ATR | Q13535 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2607452 | 0.86 | PTGS2 (0.49) | CYP3A4CYP1A2ALDH1A1CYP2C9HSD17B10 | |
| SCHEMBL2607449 | 0.84 | CYP1A2 (0.53) | CYP3A4CYP1A2ALDH1A1CYP2C9HSD17B10 | |
| SCHEMBL3439936 | 0.83 | AOC3 (0.43) | PTGS2ATR | |
| SCHEMBL2602446 | 0.82 | PTGS2 (0.38) | PTGS2 | |
| SCHEMBL2607446 | 0.79 | CYP1A2 (0.51) | CYP3A4CYP1A2ALDH1A1CYP2C9HSD17B10 | |
| SCHEMBL2607565 | 0.79 | CYP1A2 (0.48) | CYP3A4CYP1A2ALDH1A1CYP2C9HSD17B10 | |
| SCHEMBL2607427 | 0.79 | CYP1A2 (0.48) | CYP3A4CYP1A2ALDH1A1CYP2C9HSD17B10 | |
| SCHEMBL2607669 | 0.79 | CYP1A2 (0.48) | CYP3A4CYP1A2ALDH1A1CYP2C9HSD17B10 | |
| SCHEMBL2607311 | 0.79 | CYP1A2 (0.45) | CYP3A4CYP1A2ALDH1A1CYP2C9HSD17B10 | |
| SCHEMBL2618386 | 0.78 | PTGS2 (0.47) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120095027-A1 | SYNTHESIS AND ANTI-PROLIFERATIVE EFFECT OF BENZIMIDAZOLE DERIVATIVES | SPELMAN COLLEGE (US) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095027-A1 | SYNTHESIS AND ANTI-PROLIFERATIVE EFFECT OF BENZIMIDAZOLE DERIVATIVES | TYMP, MKI67, CCNI | CYP3A4 641/4885CYP1A2 1466/4885ALDH1A1 864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.