Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 10/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | USP2 | O75604 | 8/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ATR | Q13535 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2607449 | 0.90 | CYP1A2 (0.53) | CYP1A2CYP3A4CYP2C9ALDH1A1HSD17B10 | |
| SCHEMBL2607452 | 0.86 | PTGS2 (0.49) | CYP1A2CYP3A4CYP2C9ALDH1A1HSD17B10 | |
| SCHEMBL2607669 | 0.85 | CYP1A2 (0.48) | CYP1A2CYP3A4CYP2C9ALDH1A1HSD17B10 | |
| SCHEMBL2607427 | 0.85 | CYP1A2 (0.48) | CYP1A2CYP3A4CYP2C9ALDH1A1HSD17B10 | |
| SCHEMBL2607446 | 0.85 | CYP1A2 (0.51) | CYP1A2CYP3A4CYP2C9ALDH1A1HSD17B10 | |
| SCHEMBL3439919 | 0.83 | ATR (0.47) | ATRPTGS2 | |
| SCHEMBL2607311 | 0.83 | CYP1A2 (0.45) | CYP1A2CYP3A4CYP2C9ALDH1A1HSD17B10 | |
| SCHEMBL2602392 | 0.81 | PTGS2 (0.57) | CYP1A2CYP2C19ATRPTGS2 | |
| SCHEMBL2602444 | 0.81 | MAPK8 (0.43) | PTGS2MEN1KMT2A | |
| SCHEMBL2607432 | 0.79 | CYP3A4 (0.41) | CYP1A2CYP3A4CYP2C9ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120095027-A1 | SYNTHESIS AND ANTI-PROLIFERATIVE EFFECT OF BENZIMIDAZOLE DERIVATIVES | SPELMAN COLLEGE (US) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095027-A1 | SYNTHESIS AND ANTI-PROLIFERATIVE EFFECT OF BENZIMIDAZOLE DERIVATIVES | TYMP, MKI67, CCNI | CYP1A2 1466/4885CYP3A4 641/4885CYP2C9 1229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.