Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 6/20 | 0.37 |
| ▸ | CASP7 | P55210 | 6/20 | 0.37 |
| ▸ | USP2 | O75604 | 5/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12725123 | 0.83 | DPP4 (0.50) | DPP4ALDH1A1GAAKDM4EMAPT | |
| SCHEMBL12725117 | 0.83 | DPP4 (0.50) | DPP4ALDH1A1GAAKDM4EMAPT | |
| SCHEMBL13146551 | 0.81 | PRKDC (0.31) | PRKDC | |
| SCHEMBL15932566 | 0.81 | DPP4 (0.46) | DPP4ALDH1A1GAAKDM4EMAPT | |
| SCHEMBL15932568 | 0.81 | DPP4 (0.46) | DPP4ALDH1A1GAAKDM4EMAPT | |
| SCHEMBL15932569 | 0.81 | DPP4 (0.46) | DPP4ALDH1A1GAAKDM4EMAPT | |
| SCHEMBL2607281 | 0.78 | PRKDC (0.33) | DPP4PRKDCALDH1A1CASP1CASP7 | |
| SCHEMBL2246884 | 0.77 | DPP4 (0.47) | DPP4PRKDCALDH1A1GAAKDM4E | |
| SCHEMBL2607288 | 0.76 | PRKDC (0.33) | DPP4PRKDCALDH1A1GAAKDM4E | |
| SCHEMBL2607453 | 0.76 | KDM4E (0.38) | DPP4PRKDCALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120095236-A1 | PYRROLOPYRROLE DERIVATIVES, THEIR MANUFACTURE AND USE AS SEMICONDUCTORS | BASF SE (DE) | 2012-04-19 | — | — | US | disclosed |
| US-20120095236-A1 | PYRROLOPYRROLE DERIVATIVES, THEIR MANUFACTURE AND USE AS SEMICONDUCTORS | BASF SE (DE) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095236-A1 | PYRROLOPYRROLE DERIVATIVES, THEIR MANUFACTURE AND USE AS SEMICONDUCTORS | PPOX, PIN1, DDT | DPP4 2747/4885PRKDC 173/4885ALDH1A1 1580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.