SCHEMBL26074789

SCHEMBL26074789

Cc1cccc2c3ccccc3n3c(-c4c(C5CCCCC5)cccc4C4CCCCC4)cnc3c12

nearest known ligand 0.33

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 1/20 0.33
CRHBP P24387 2/20 0.33
CRHR2 Q13324 2/20 0.33
MEN1 O00255 1/20 0.33
LMNA P02545 1/20 0.33
XBP1 P17861 1/20 0.33
MAPK1 P28482 1/20 0.33
KMT2A Q03164 1/20 0.33
DRD1 P21728 6/20 0.32
DRD5 P21918 6/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
RXFP1 Q9HBX9 1/20 0.31
PDK2 Q15119 3/20 0.30
PDK4 Q16654 2/20 0.30
CCNE1 P24864 1/20 0.30
CDK2 P24941 1/20 0.30
PDK1 Q15118 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19237041 0.86 TNF (0.32) TLR7CRHBPCRHR2MEN1LMNA
SCHEMBL13287048 0.86 TLR7 (0.34) TLR7CRHBPCRHR2MEN1LMNA
SCHEMBL13286946 0.86 TLR7 (0.34) TLR7CRHBPCRHR2MEN1LMNA
SCHEMBL19258032 0.82 ALKBH5 (0.37) MEN1LMNAMAPK1KMT2ASMN1; SMN2
SCHEMBL25551780 0.77
SCHEMBL20306455 0.77 CNR1 (0.33) TLR7LMNADRD1DRD5
SCHEMBL27433415 0.76
SCHEMBL25551778 0.76 CYP17A1 (0.34) MEN1KMT2A
SCHEMBL13287105 0.76 CYP1A2 (0.32)
SCHEMBL13287044 0.75 SLC22A12 (0.32) PDK2PDK4PDK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-02-29 US disclosed
US-20230303602-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, OCIAD2, OSBP TLR7 1257/4885CRHBP 4017/4885CRHR2 4533/4885
US-20230303602-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ODC1 TLR7 2337/4885CRHBP 2978/4885CRHR2 3432/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.