SCHEMBL19258032

SCHEMBL19258032

Cc1cccc(C)c1-c1cnc2c3c(C)cccc3c3ccccc3n12

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALKBH5 Q6P6C2 1/20 0.37
FTO Q9C0B1 1/20 0.37
MAPT P10636 5/20 0.33
KDM4E B2RXH2 3/20 0.33
WEE1 P30291 1/20 0.32
LMNA P02545 3/20 0.32
MEN1 O00255 2/20 0.32
GAA P10253 2/20 0.32
KMT2A Q03164 2/20 0.32
PTGER4 P35408 2/20 0.32
HPGD P15428 2/20 0.32
NTRK1 P04629 1/20 0.32
HTT P42858 1/20 0.32
GABRP O00591 1/20 0.32
GABRD O14764 1/20 0.32
GABRA1 P14867 1/20 0.32
GABRB1 P18505 1/20 0.32
GABRG2 P18507 1/20 0.32
GABRB3 P28472 1/20 0.32
GABRA5 P31644 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12759718 0.89 NPC1 (0.36) ALKBH5FTOWEE1MEN1KMT2A
SCHEMBL12759482 0.88 ALKBH5 (0.39) ALKBH5FTOMAPTKDM4EWEE1
SCHEMBL25551778 0.87 CYP17A1 (0.34) ALKBH5FTOKDM4EMEN1KMT2A
SCHEMBL17689164 0.87 CYP2C9 (0.34) MAPTLMNAMEN1KMT2AIDO1
SCHEMBL18828225 0.84 ALOX5AP (0.33) ALKBH5FTOMAPTLMNAMEN1
SCHEMBL26074789 0.82 TLR7 (0.33) LMNAMEN1KMT2AMAPK1SMN1; SMN2
SCHEMBL21141862 0.80 ALOX5AP (0.31)
SCHEMBL19595218 0.80 NPC1 (0.37) ALKBH5FTOMAPTKDM4EWEE1
SCHEMBL12077046 0.79 BAZ2B (0.34) ALKBH5FTOMAPTLMNAMEN1
SCHEMBL29807954 0.79 BAZ2B (0.34) ALKBH5FTOMAPTLMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-04 US disclosed
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-02-29 US disclosed
US-20230180594-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-06-08 US disclosed
EP-3205658-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2017-08-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230180594-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, LBR, OCIAD1 ALKBH5 2770/4885FTO 1293/4885MAPT 4065/4885
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, OCIAD2, OSBP ALKBH5 2192/4885FTO 309/4885MAPT 1707/4885
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ICOSLG ALKBH5 475/4885FTO 48/4885MAPT 1653/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.