Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | CCR2 | P41597 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | IDH1 | O75874 | 1/20 | 0.42 |
| ▸ | ACLY | P53396 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26074500 | 0.90 | GAA (0.44) | PTGES2CYP2C19MCL1ALDH1A1LMNA | |
| SCHEMBL26074499 | 0.85 | TSHR (0.48) | PTGES2CCR2ALDH1A1LMNATSHR | |
| SCHEMBL26074505 | 0.80 | MRGPRX1 (0.53) | PTGES2MCL1MAPTIDH1ACLY | |
| SCHEMBL3020003 | 0.79 | PTGES2 (0.53) | PTGES2CYP2C19CYP2C9CCR2ERN1 | |
| SCHEMBL26074502 | 0.78 | SLC40A1 (0.43) | PTGES2CYP2C19CCR2ERN1IDH1 | |
| SCHEMBL25450295 | 0.77 | MCL1 (0.51) | PTGES2CYP2C19MCL1CCR2ALDH1A1 | |
| SCHEMBL22531925 | 0.77 | MCL1 (0.51) | PTGES2CYP2C19MCL1CCR2ALDH1A1 | |
| SCHEMBL26075677 | 0.77 | ALDH1A1 (0.51) | PTGES2CYP2C19MCL1CCR2ALDH1A1 | |
| SCHEMBL26074503 | 0.76 | SLC22A12 (0.60) | CYP2C19CYP2C9ALDH1A1CYP3A4TSHR | |
| SCHEMBL30161625 | 0.76 | PTGES2 (0.50) | PTGES2CYP2C19CYP2C9CCR2ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230303570-A1 | KINASE INHIBITORS AND USES THEREOF | ABM THERAPEUTICS CORP (US) | 2023-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230303570-A1 | KINASE INHIBITORS AND USES THEREOF | ERBB2, ERBB3, ERBB4 | PTGES2 1727/4885CYP2C19 1484/4885MCL1 784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.