SCHEMBL260762

SCHEMBL260762

C=C1CC[C@](O)(OO)C/C1=C/C=C1CCC[C@@]2(C)C1CC[C@@H]2[C@H](C)CCCC(C)C

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.69
VDR P11473 4/20 0.69
MEN1 O00255 3/20 0.69
KMT2A Q03164 3/20 0.69
ADORA3 P0DMS8 3/20 0.69
CDC25A P30304 3/20 0.69
ALDH1A1 P00352 2/20 0.69
CYP3A4 P08684 2/20 0.69
ALOX15 P16050 2/20 0.69
SMN1; SMN2 Q16637 2/20 0.69
PGR P06401 2/20 0.69
TDP1 Q9NUW8 1/20 0.69
HSPD1 P10809 1/20 0.69
HPGD P15428 1/20 0.69
TBXA2R P21731 1/20 0.69
PTGS1 P23219 1/20 0.69
GLRA1 P23415 1/20 0.69
DRD3 P35462 1/20 0.69
HSPE1 P61604 1/20 0.69
HSD17B10 Q99714 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6842113 1.00 MAPT (0.69) MAPTVDRMEN1KMT2AADORA3
SCHEMBL10034118 1.00 MAPT (0.69) MAPTVDRMEN1KMT2AADORA3
SCHEMBL3698818 1.00 MAPT (0.69) MAPTVDRMEN1KMT2AADORA3
Acetic Acid SCHEMBL5184154 0.96 MAPT (0.64) MAPTVDRMEN1KMT2AADORA3
SCHEMBL233428 0.93 MAPT (0.69) MAPTVDRMEN1KMT2AADORA3
SCHEMBL10594420 0.91 VDR (0.57) MAPTVDRMEN1KMT2AADORA3
SCHEMBL4960177 0.89 MAPT (0.74) MAPTVDRMEN1KMT2AADORA3
SCHEMBL8003899 0.89 MAPT (0.74) MAPTVDRMEN1KMT2AADORA3
SCHEMBL232217 0.89 MAPT (0.74) MAPTVDRMEN1KMT2AADORA3
SCHEMBL10034122 0.89 MAPT (0.74) MAPTVDRMEN1KMT2AADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2527 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260116861-A1 ISOXAZOLE HYDROXAMIC ACIDS AS HISTONE DEACETYLASE 6 INHIBITORS THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION (US) 2026-04-30 US claimed
US-12522572-B2 Isoxazole hydroxamic acids as histone deacetylase 6 inhibitors THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION (US) 2026-01-13 US claimed
WO-2025108575-A1 METHODS OF SELECTIVE DEPROTECTION AND SYNTHESIS OF TRANSHYDRINDANE- SKELETON-BASED COMPOUNDS ROCHE DIAGNOSTICS GMBH (DE) 2025-05-30 WO claimed
WO-2025058988-A1 METHOD OF TREATING NON-IMMUNOGENIC SKIN CANCERS THE GENERAL HOSPITAL CORPORATION (US) 2025-03-20 WO claimed
WO-2024227063-A1 METHODS AND COMPOSITIONS FOR TREATING OBESITY, SKIN DISORDERS, AND/OR EYE DISORDERS THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2024-10-31 WO claimed
US-20240343697-A1 ISOXAZOLE HYDROXAMIC ACIDS AS HISTONE DEACETYLASE 6 INHIBITORS THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION (US) 2024-10-17 US claimed
CN-111480080-B Method for improving therapeutic cell quality by real-time glutathione measurement 塞尔吐温株式会社 2023-09-19 CN claimed
US-20230242480-A1 Alkyne Compound, Vitamin D Compound, Analytical Method, and Production Method JEOL LTD. (JP) 2023-08-03 US claimed
EP-4212498-A2 ALKYNE COMPOUND, VITAMIN D COMPOUND, ANALYTICAL METHOD, AND PRODUCTION METHOD Tokyo University of Agriculture and Technology (JP) 2023-07-19 EP claimed
CN-116425661-A Alkyne compounds, vitamin D compounds, analytical methods and manufacturing methods 国立大学法人东京农工大学 2023-07-14 CN claimed
EP-0588539-B1 Stabilized pharmaceutical compositions containing derivatives of vitamins D2 and D3 TEVA PHARMA (IL) 1997-02-05 EP claimed
WO-1996036340-A1 STABLE AQUEOUS FORMULATIONS OF 1α,25-DIHYDROXYCHOLECALCIFEROL FOR PARENTERAL ADMINISTRATION ABBOTT LABORATORIES (US) 1996-11-21 WO claimed
EP-0437225-B1 Topical preparations HOFFMANN LA ROCHE (CH) 1994-04-20 EP claimed
EP-0477270-A1 PREVENTION AND TREATMENT OF MICROBIAL INFECTION BY PHOSPHOGLYCERIDES MED-TAL, INC. (US) 1992-04-01 EP claimed
WO-1990015609-A1 PREVENTION AND TREATMENT OF MICROBIAL INFECTION BY PHOSPHOGLYCERIDES MED-TAL, INC. (US) 1990-12-27 WO claimed
EP-0313703-A1 Use of 24,25-dihydroxycholecalciferole in the treatment of urinary calculus KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1989-05-03 EP claimed
EP-0301167-A1 A combination of cholecalciferol derivatives for the treatment of renal bone disease Teva Pharmaceutical Industries Limited (IL) 1989-02-01 EP claimed
EP-0230600-A1 Production of cholecalciferol derivatives and novel intermediates used therefor Teva Pharmaceutical Industries Limited (IL) 1987-08-05 EP claimed
US-4617297-A CALCIUM METABOLIC DISORDERS HOFFMANN-LA ROCHE INC. (US) 1986-10-14 US claimed
US-4612308-A ANTITUMOR AND ANTILEUKEMIA AGENTS, OSTEOPOROSIS HOFFMANN-LA ROCHE INC. (US) 1986-09-16 US claimed