Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.69 |
| ▸ | VDR | P11473 | 4/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.69 |
| ▸ | CDC25A | P30304 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | PGR | P06401 | 2/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.69 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.69 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.69 |
| ▸ | DRD3 | P35462 | 1/20 | 0.69 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL260762 | 1.00 | MAPT (0.69) | MAPTVDRMEN1KMT2AADORA3 | |
| SCHEMBL10034118 | 1.00 | MAPT (0.69) | MAPTVDRMEN1KMT2AADORA3 | |
| SCHEMBL3698818 | 1.00 | MAPT (0.69) | MAPTVDRMEN1KMT2AADORA3 | |
| Acetic Acid SCHEMBL5184154 | 0.96 | MAPT (0.64) | MAPTVDRMEN1KMT2AADORA3 | |
| SCHEMBL233428 | 0.93 | MAPT (0.69) | MAPTVDRMEN1KMT2AADORA3 | |
| SCHEMBL10594420 | 0.91 | VDR (0.57) | MAPTVDRMEN1KMT2AADORA3 | |
| SCHEMBL4960177 | 0.89 | MAPT (0.74) | MAPTVDRMEN1KMT2AADORA3 | |
| SCHEMBL8003899 | 0.89 | MAPT (0.74) | MAPTVDRMEN1KMT2AADORA3 | |
| SCHEMBL232217 | 0.89 | MAPT (0.74) | MAPTVDRMEN1KMT2AADORA3 | |
| SCHEMBL10034122 | 0.89 | MAPT (0.74) | MAPTVDRMEN1KMT2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3015107-A1 | AGENT FOR TREATING MEIBOMIAN GLAND DYSFUNCTION | Keio University (JP) | 2016-05-04 | — | — | EP | disclosed |
| US-20040116724-A1 | Stereoselective synthesis of 24-hydroxylated compounds useful for the preparation of aminosterols, vitamin D analogs, and other compounds | KINNEY WILLIAM A (US) | 2004-06-17 | — | — | US | disclosed |
| EP-1047671-A1 | METHOD OF PREPARATION OF CHOLECALCIFEROL DERIVATIVES AND NEW INTERMEDIATE COMPOUNDS | INSTYTUT FARMACEUTYCZNY (PL) | 2000-11-02 | — | — | EP | disclosed |
| EP-0998931-A1 | REMEDIES FOR DRY EYE | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2000-05-10 | — | — | EP | disclosed |
| WO-1999036400-A1 | METHOD OF PREPARATION OF CHOLECALCIFEROL DERIVATIVES AND NEW INTERMEDIATE COMPOUNDS | INSTYTUT FARMACEUTYCZNY (PL) | 1999-07-22 | — | — | WO | disclosed |
| US-4594340-A | Antitumor agent | HOFFMANN-LA ROCHE INC. (US) | 1986-06-10 | — | — | US | disclosed |