Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PRKCG | P05129 | 1/20 | 0.31 |
| ▸ | PRKCB | P05771 | 1/20 | 0.31 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.30 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16320942 | 0.95 | ALDH1A1 (0.37) | ALDH1A1CHRNA7HRH3PKMKDM4E | |
| SCHEMBL10237822 | 0.93 | ALDH1A1 (0.38) | ALDH1A1CHRNA7HRH3PKMKDM4E | |
| SCHEMBL23710822 | 0.91 | ALDH1A1 (0.36) | ALDH1A1CHRNA7HRH3PKMMAPT | |
| SCHEMBL441543 | 0.90 | PRKCG (0.37) | ALDH1A1CHRNA7HRH3PKMKDM4E | |
| SCHEMBL12660326 | 0.83 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL57304 | 0.81 | — | — | |
| SCHEMBL4911003 | 0.81 | — | — | |
| SCHEMBL24496310 | 0.81 | CHRNA7 (0.42) | ALDH1A1CHRNA7HRH3PKMKDM4E | |
| SCHEMBL12045016 | 0.80 | — | — | |
| SCHEMBL21954031 | 0.78 | HRH3 (0.38) | ALDH1A1CHRNA7HRH3PKMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023180484-A1 | ANTIBODY-CONJUGATES FOR TARGETING OF TUMOURS EXPRESSING PTK7 | SYNAFFIX B.V. (NL) | 2023-09-28 | — | — | WO | disclosed |