Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 13/20 | 0.43 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26077209 | 0.88 | FURIN (0.54) | FURIN | |
| SCHEMBL26077213 | 0.88 | FURIN (0.54) | FURIN | |
| SCHEMBL26077225 | 0.87 | FURIN (0.49) | FURIN | |
| SCHEMBL29891169 | 0.86 | GPR119 (0.47) | FURINGPR119 | |
| SCHEMBL21551166 | 0.86 | GPR119 (0.47) | FURINGPR119 | |
| SCHEMBL26077230 | 0.85 | FURIN (0.45) | FURINFFAR4 | |
| SCHEMBL26077239 | 0.81 | FURIN (0.42) | FURIN | |
| SCHEMBL21550924 | 0.80 | FURIN (0.62) | FURIN | |
| SCHEMBL26077250 | 0.79 | FURIN (0.55) | FURIN | |
| SCHEMBL26077229 | 0.79 | FURIN (0.41) | FURIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11773078-B2 | Furin inhibitors | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11773078-B2 | Furin inhibitors | FURIN, TGFB1, PCSK7 | FURIN 1/4885PLA2G7 448/4885FFAR4 4258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.