Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 7/20 | 0.40 |
| ▸ | CNR2 | P34972 | 5/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | SGK1 | O00141 | 3/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21551454 | 0.90 | FURIN (0.42) | FURINSCN9AGPR119 | |
| SCHEMBL21551615 | 0.86 | GPR119 (0.49) | FURINGPR119 | |
| SCHEMBL29890881 | 0.86 | GPR119 (0.49) | FURINGPR119 | |
| SCHEMBL26077449 | 0.85 | FURIN (0.40) | FURINCNR2SCN9ACSF1RDAPK1 | |
| SCHEMBL26077448 | 0.84 | FURIN (0.37) | FURINCNR2CSF1RDAPK1 | |
| SCHEMBL26077219 | 0.82 | FURIN (0.53) | FURINCNR2 | |
| SCHEMBL26077247 | 0.79 | CNR2 (0.39) | FURINCNR2GPR119 | |
| SCHEMBL26077440 | 0.79 | FURIN (0.42) | FURINCNR2 | |
| SCHEMBL26077451 | 0.77 | FURIN (0.53) | FURIN | |
| SCHEMBL26077353 | 0.77 | FURIN (0.41) | FURINCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11773078-B2 | Furin inhibitors | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11773078-B2 | Furin inhibitors | FURIN, TGFB1, PCSK7 | FURIN 1/4885CNR2 4165/4885SCN9A 1845/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.