SCHEMBL2607777

SCHEMBL2607777

CCCSc1cccc2ccccc12

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IFNAR1 P17181 1/20 0.45
PTGS2 P35354 1/20 0.45
ALDH1A1 P00352 3/20 0.44
LMNA P02545 2/20 0.44
MAPK1 P28482 2/20 0.44
NPY1R P25929 1/20 0.44
NPY2R P49146 1/20 0.44
HDAC3 O15379 1/20 0.40
HDAC4 P56524 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC7 Q8WUI4 1/20 0.40
HDAC2 Q92769 1/20 0.40
HDAC10 Q969S8 1/20 0.40
HDAC11 Q96DB2 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
HDAC9 Q9UKV0 1/20 0.40
HDAC5 Q9UQL6 1/20 0.40
CYP2A6 P11509 1/20 0.40
CYP1A2 P05177 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2607673 0.89 TLR8 (0.50) IFNAR1PTGS2ALDH1A1LMNAMAPK1
SCHEMBL30417186 0.87 PTGS2 (0.49) IFNAR1PTGS2ALDH1A1LMNAMAPK1
SCHEMBL18758015 0.87 PTGS2 (0.49) IFNAR1PTGS2ALDH1A1LMNAMAPK1
SCHEMBL5316461 0.85 PTGS2 (0.50) IFNAR1PTGS2ALDH1A1LMNAMAPK1
SCHEMBL25738323 0.85 PTGS2 (0.50) IFNAR1PTGS2ALDH1A1LMNAMAPK1
SCHEMBL1057367 0.83 IFNAR1 (0.47) IFNAR1ALDH1A1LMNAMAPK1NPY1R
SCHEMBL6293960 0.83 IFNAR1 (0.43) IFNAR1ALDH1A1LMNAMAPK1NPY1R
SCHEMBL6835641 0.83 PTGS2 (0.41) PTGS2ALDH1A1CYP2A6CYP1A2PDE5A
Hydrochloric Acid SCHEMBL11283634 0.81 HTR1B (0.50) IFNAR1ALDH1A1LMNAMAPK1NPY1R
SCHEMBL30548746 0.80 PTGS2 (0.55) PTGS2ALDH1A1MAPK1PDE5ATLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111517902-B Aerobic oxidation system containing sulfinic acid, sulfonic acid or derivatives thereof and photo-oxidation promoting method thereof 清华大学 2022-06-14 CN disclosed
CN-111517902-A Aerobic oxidation system containing sulfinic acid, sulfonic acid or derivatives thereof and photo-oxidation promoting method thereof 清华大学 2020-08-11 CN disclosed
US-8828629-B2 Black curable composition, light-shielding color filter for a solid-state imaging device and method of producing the same, solid-state imaging device, wafer level lens, and camera module FUJIFILM CORPORATION (JP) 2014-09-09 US disclosed
US-8828629-B2 Black curable composition, light-shielding color filter for a solid-state imaging device and method of producing the same, solid-state imaging device, wafer level lens, and camera module FUJIFILM CORPORATION (JP) 2014-09-09 US disclosed
US-20130123326-A1 ALLOSTERIC BINDING COMPOUNDS REGION MIDTJYLLAND (DK) 2013-05-16 US disclosed
US-20130123326-A1 ALLOSTERIC BINDING COMPOUNDS REGION MIDTJYLLAND (DK) 2013-05-16 US disclosed
US-20130028587-A1 BLACK CURABLE COMPOSITION, LIGHT-SHIELDING COLOR FILTER FOR A SOLID-STATE IMAGING DEVICE AND METHOD OF PRODUCING THE SAME, SOLID-STATE IMAGING DEVICE, WAFER LEVEL LENS, AND CAMERA MODULE FUJIFILM CORPORATION (JP) 2013-01-31 US disclosed
US-20130028587-A1 BLACK CURABLE COMPOSITION, LIGHT-SHIELDING COLOR FILTER FOR A SOLID-STATE IMAGING DEVICE AND METHOD OF PRODUCING THE SAME, SOLID-STATE IMAGING DEVICE, WAFER LEVEL LENS, AND CAMERA MODULE FUJIFILM CORPORATION (JP) 2013-01-31 US disclosed
US-20120095048-A1 ALLOSTERIC BINDING COMPOUNDS REGION MIDT JYLLAND (DK) 2012-04-19 US disclosed
US-20120095048-A1 ALLOSTERIC BINDING COMPOUNDS REGION MIDT JYLLAND (DK) 2012-04-19 US disclosed
US-8119311-B2 Photosensitive resin composition, light-shielding color filter and production process therefor, and image sensor FUJIFILM CORPORATION (JP) 2012-02-21 US disclosed
US-8119311-B2 Photosensitive resin composition, light-shielding color filter and production process therefor, and image sensor FUJIFILM CORPORATION (JP) 2012-02-21 US disclosed
US-8110324-B2 Photosensitive resin composition, light-shielding color filter and production process therefor, and image sensor FUJIFILM CORPORATION (JP) 2012-02-07 US disclosed
US-8110324-B2 Photosensitive resin composition, light-shielding color filter and production process therefor, and image sensor FUJIFILM CORPORATION (JP) 2012-02-07 US disclosed
WO-2010094289-A1 ALLOSTERIC BINDING COMPOUNDS AARHUS UNIVERSITET (DK) 2010-08-26 WO disclosed
US-20090246651-A1 PHOTOSENSITIVE RESIN COMPOSITION, LIGHT-SHIELDING COLOR FILTER AND PRODUCTION PROCESS THEREFOR, AND IMAGE SENSOR FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
US-20090246651-A1 PHOTOSENSITIVE RESIN COMPOSITION, LIGHT-SHIELDING COLOR FILTER AND PRODUCTION PROCESS THEREFOR, AND IMAGE SENSOR FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
US-20090246650-A1 PHOTOSENSITIVE RESIN COMPOSITION, LIGHT-SHIELDING COLOR FILTER AND PRODUCTION PROCESS THEREFOR, AND IMAGE SENSOR FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
US-20090246650-A1 PHOTOSENSITIVE RESIN COMPOSITION, LIGHT-SHIELDING COLOR FILTER AND PRODUCTION PROCESS THEREFOR, AND IMAGE SENSOR FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
EP-2105792-A1 Photosensitive resin composition, light-shielding color filter and production process therefor, and image sensor FUJIFILM Corporation (JP) 2009-09-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120095048-A1 ALLOSTERIC BINDING COMPOUNDS GRIN2C, GRM2, GRIN2B IFNAR1 2195/4885PTGS2 3193/4885ALDH1A1 3676/4885
US-20130123326-A1 ALLOSTERIC BINDING COMPOUNDS GRIN2C, GRM2, GRIN2B IFNAR1 2195/4885PTGS2 3193/4885ALDH1A1 3676/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.