Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.50 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.45 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | SOAT1 | P35610 | 8/20 | 0.41 |
| ▸ | IFNAR1 | P17181 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25738323 | 1.00 | PTGS2 (0.50) | PTGS2CYSLTR2CYSLTR1TLR8EPHX2 | |
| SCHEMBL30417186 | 0.98 | PTGS2 (0.49) | PTGS2CYSLTR2CYSLTR1TLR8EPHX2 | |
| SCHEMBL18758015 | 0.98 | PTGS2 (0.49) | PTGS2CYSLTR2CYSLTR1TLR8EPHX2 | |
| SCHEMBL2607673 | 0.93 | TLR8 (0.50) | PTGS2TLR8IFNAR1NPC1ALDH1A1 | |
| SCHEMBL2607777 | 0.85 | IFNAR1 (0.45) | PTGS2TLR8IFNAR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6293960 | 0.85 | IFNAR1 (0.43) | IFNAR1NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL8048467 | 0.84 | PTGS2 (0.49) | PTGS2CYSLTR2CYSLTR1TLR8EPHX2 | |
| SCHEMBL8573907 | 0.83 | IFNAR1 (0.39) | PTGS2IFNAR1KDM4ENPC1ALDH1A1 | |
| SCHEMBL9850477 | 0.83 | PTGS2 (0.46) | PTGS2CYSLTR2CYSLTR1TLR8EPHX2 | |
| SCHEMBL8741439 | 0.83 | PTGS2 (0.50) | PTGS2CYSLTR2CYSLTR1TLR8EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007064869-A2 | CATALYSTS FOR ARYL SULFIDE SYNTHESIS AND METHOD OF PRODUCING ARYL SULFIDES | YALE UNIVERSITY (US) | 2007-06-07 | — | — | WO | disclosed |
| WO-1998005721-A1 | POLYESTER BASED OPTICAL FIBER COATINGS | ALLIEDSIGNAL INC. (US) | 1998-02-12 | — | — | WO | disclosed |
| US-5672675-A | Vinyl ether-terminated polyester oligomer stabilizers for vinyl ether-based coating systems | ALLIEDSIGNAL, INC. (US) | 1997-09-30 | — | — | US | disclosed |
| US-5514727-A | OPTICAL FIBER COATINGS, POLYETHER OR POLYESTER POLYOLS ENDCAPPED WITH HYDROXY VINYL ETHER | ALLIEDSIGNAL INC. (US) | 1996-05-07 | — | — | US | disclosed |
| WO-1996006142-A1 | POLYESTER BASED OPTICAL FIBER COATINGS | ALLIEDSIGNAL INC. (US) | 1996-02-29 | — | — | WO | disclosed |