Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30931757 | 1.00 | PPM1B (0.46) | PPM1BPTPN1PPP1CCMAPTPKM | |
| SCHEMBL28556040 | 1.00 | PPM1B (0.46) | PPM1BPTPN1PPP1CCMAPTPKM | |
| SCHEMBL28548780 | 1.00 | PPM1B (0.46) | PPM1BPTPN1PPP1CCMAPTPKM | |
| SCHEMBL17520184 | 0.91 | MAPT (0.46) | PPM1BPTPN1PPP1CCMAPTPKM | |
| Hydrochloric Acid SCHEMBL21724406 | 0.90 | MAPT (0.48) | PPM1BPTPN1PPP1CCMAPTPKM | |
| SCHEMBL15712143 | 0.86 | PPM1B (0.53) | PPM1BPTPN1PPP1CCMAPTHSD11B1 | |
| SCHEMBL25467328 | 0.82 | PPM1B (0.50) | PPM1BPTPN1PPP1CCMAPTHSD11B1 | |
| SCHEMBL9843585 | 0.82 | PPM1B (0.50) | PPM1BPTPN1PPP1CCMAPTHSD11B1 | |
| SCHEMBL9537641 | 0.82 | PPM1B (0.50) | PPM1BPTPN1PPP1CCMAPTHSD11B1 | |
| SCHEMBL5791356 | 0.82 | PPM1B (0.50) | PPM1BPTPN1PPP1CCMAPTHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11773078-B2 | Furin inhibitors | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11773078-B2 | Furin inhibitors | FURIN, TGFB1, PCSK7 | PPM1B 3687/4885PTPN1 4412/4885PPP1CC 4666/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.