Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 5/20 | 0.80 |
| ▸ | BRD4 | O60885 | 6/20 | 0.76 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | BRD2 | P25440 | 4/20 | 0.59 |
| ▸ | BRD3 | Q15059 | 4/20 | 0.59 |
| ▸ | BRDT | Q58F21 | 4/20 | 0.59 |
| ▸ | PPARG | P37231 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1422009 | 0.89 | ABCB1 (1.00) | ABCB1BRD4MEN1KMT2AKDM4E | |
| SCHEMBL29465904 | 0.89 | ABCB1 (1.00) | ABCB1BRD4MEN1KMT2AKDM4E | |
| SCHEMBL20271922 | 0.88 | BRD4 (0.71) | ABCB1BRD4MEN1KMT2AKDM4E | |
| SCHEMBL4165061 | 0.87 | ABCB1 (0.81) | ABCB1BRD4MEN1KMT2AKDM4E | |
| SCHEMBL20271941 | 0.87 | BRD4 (1.00) | ABCB1BRD4MEN1KMT2AKDM4E | |
| SCHEMBL30599697 | 0.87 | BRD4 (1.00) | ABCB1BRD4MEN1KMT2AKDM4E | |
| SCHEMBL20270787 | 0.85 | BRD4 (0.73) | ABCB1BRD4MEN1KMT2AKDM4E | |
| SCHEMBL20271547 | 0.84 | BRD4 (0.72) | ABCB1BRD4MEN1KMT2AKDM4E | |
| SCHEMBL20271549 | 0.84 | BRD4 (0.72) | ABCB1BRD4MEN1KMT2AKDM4E | |
| SCHEMBL16894639 | 0.83 | ABCB1 (0.83) | ABCB1BRD4MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3554503-B1 | INHIBITORS OF BROMODOMAIN-CONTAINING PROTEIN 4 (BRD4) | UNIV TEXAS (US) | 2023-10-04 | — | — | EP | disclosed |