Sugi Predict

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SCHEMBL1422009

SCHEMBL1422009

COc1cc(OC)c2c(=O)cc(-c3cc(OC)c(OC)c(OC)c3)oc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ABCB1 P08183 4/20 1.00
▸ MEN1 O00255 4/20 0.71
▸ KMT2A Q03164 4/20 0.71
▸ KDM4E B2RXH2 4/20 0.71
▸ ALDH1A1 P00352 3/20 0.71
▸ ABCG2 Q9UNQ0 2/20 0.71
▸ NPC1 O15118 1/20 0.71
▸ RAB9A P51151 1/20 0.71
▸ ADORA3 P0DMS8 2/20 0.65
▸ BRD4 O60885 1/20 0.65
▸ POLB P06746 2/20 0.64
▸ MAPT P10636 2/20 0.64
▸ RECQL P46063 1/20 0.64
▸ PPARG P37231 1/20 0.62
▸ TP53 P04637 1/20 0.61
▸ MDM2 Q00987 1/20 0.61
▸ FLT3 P36888 1/20 0.60
▸ CYP3A4 P08684 1/20 0.56
▸ CYP1A1 P04798 2/20 0.56
▸ CYP1A2 P05177 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29465904 1.00 ABCB1 (1.00) ABCB1MEN1KMT2AKDM4EALDH1A1
SCHEMBL16894639 0.91 ABCB1 (0.83) ABCB1MEN1KMT2AKDM4EALDH1A1
SCHEMBL4165061 0.90 ABCB1 (0.81) ABCB1MEN1KMT2AKDM4EALDH1A1
SCHEMBL26079993 0.89 ABCB1 (0.80) ABCB1MEN1KMT2AKDM4EALDH1A1
SCHEMBL16894624 0.88 ABCB1 (0.79) ABCB1MEN1KMT2AKDM4EALDH1A1
Corymbosin SCHEMBL29426420 0.88 ABCB1 (0.78) ABCB1MEN1KMT2AKDM4EALDH1A1
Corymbosin SCHEMBL1976826 0.88 ABCB1 (0.78) ABCB1MEN1KMT2AKDM4EALDH1A1
SCHEMBL1676018 0.87 ABCB1 (0.78) ABCB1MEN1KMT2AKDM4EALDH1A1
SCHEMBL1765114 0.87 ABCB1 (1.00) ABCB1MEN1KMT2AKDM4EALDH1A1
SCHEMBL16894650 0.86 ABCB1 (0.76) ABCB1MEN1KMT2AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116953125-A Separation method and content determination method of chemical components in Murraya paniculata 华润三九医药股份有限公司 2023-10-27 — — CN claimed
US-20220003753-A1 METABOLIC PROFILING FOR THE DIAGNOSIS OF A SUBSET OF IDIOPATHIC AUTISM SPECTRUM DISORDER PATIENTS, ADS PHENOTYPE 1 STALICLA SA (CH) 2022-01-06 — — US claimed
CN-111617076-B Compound pharmaceutical composition containing arbidol hydrochloride and application thereof 江苏吴中医药集团有限公司 2021-09-28 — — CN claimed
US-20210169993-A1 TREATMENT OF A SUBTYPE OF ASD STALICLA SA (CH) 2021-06-10 — — US claimed
CN-111617076-A Compound pharmaceutical composition containing arbidol hydrochloride and application thereof 江苏吴中医药集团有限公司 2020-09-04 — — CN claimed
CN-111511407-A Treatment of ASD subtypes 斯大利卡拉公司 2020-08-07 — — CN claimed
CN-111374970-A Composition with anti-colitis activity and application thereof 广西壮族自治区中医药研究院 2020-07-07 — — CN claimed
US-9669003-B2 Use of flavone and flavanone derivatives in preparation of sedative and hypnotic drugs JIN YONGRI (CN) 2017-06-06 — — US claimed
US-20150196529-A1 USE OF FLAVONE AND FLAVANONE DERIVATIVES IN PREPARATION OF SEDATIVE AND HYPNOTIC DRUGS JIN YONGRI (CN) 2015-07-16 — — US claimed
US-6872771-B1 Tire with rubber containing flavone THE GOODYEAR TIRE & RUBBER COMPANY (US) 2005-03-29 — — US claimed
JP-2003504327-A — — 2003-02-04 — — JP claimed
EP-1223928-A2 USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS Prendergast, Patrick Thomas (IE) 2002-07-24 — — EP claimed
WO-2001003681-A2 USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS PRENDERGAST PATRICK T (IE) 2001-01-18 — — WO claimed
US-12474327-B2 Metabolic profiling for the diagnosis of a subset of idiopathic autism spectrum disorder patients, ADS Phenotype 1 STALICLA SA (CH) 2025-11-18 — — US disclosed
US-20250262155-A1 LITHE LIPOSOMES COMPRISING ABSORPTION ENHANCERS FOR ORAL DRUG DELIVERY Aspire LLC (US) 2025-08-21 — — US disclosed
CN-116953125-A Separation method and content determination method of chemical components in Murraya paniculata 华润三九医药股份有限公司 2023-10-27 — — CN disclosed
US-20030125264-A1 Methods For Treating Wounds KIMBERLY-CLARK WORLDWIDE, INC. 2003-07-03 — — US disclosed
US-6555523-B1 Such as 3',4'-diacetoxy-5,6,7-trimethoxyflavone or naringin in the treatment HIV, picornavirus, and/or respiratory virus CASCADE ESTATES LTD. (MU) 2003-04-29 — — US disclosed
EP-1298115-A1 PROCESS FOR THE PREPARATION OF POLYHYDRIC ALCOHOLS National Institute of Advanced Industrial Science and Technology (JP) 2003-04-02 — — EP disclosed
US-20020157939-A1 Process for preparation of polyhydric alcohols NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2002-10-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030125264-A1 Methods For Treating Wounds FGF2, MMP1, FIBP ABCB1 2498/4885MEN1 3867/4885KMT2A 4306/4885
US-20150196529-A1 USE OF FLAVONE AND FLAVANONE DERIVATIVES IN PREPARATION OF SEDATIVE AND HYPNOTIC DRUGS CYP2D6, GATAD2A, CYP3A43 ABCB1 218/4885MEN1 3778/4885KMT2A 499/4885
US-20020157939-A1 Process for preparation of polyhydric alcohols ADH1C, ADH1A, ADH5 ABCB1 4875/4885MEN1 233/4885KMT2A 1046/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.