SCHEMBL26080853

SCHEMBL26080853

O=C(O)/C=C/c1ccc(-n2c3ccccc3c3ccccc32)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 4/20 0.56
HDAC6 Q9UBN7 4/20 0.56
HDAC3 O15379 3/20 0.56
HDAC1 Q13547 3/20 0.56
HDAC2 Q92769 3/20 0.56
HDAC8 Q9BY41 3/20 0.56
HCAR2 Q8TDS4 2/20 0.56
HDAC7 Q8WUI4 2/20 0.56
HDAC10 Q969S8 2/20 0.56
HDAC11 Q96DB2 2/20 0.56
HDAC9 Q9UKV0 2/20 0.56
HDAC5 Q9UQL6 2/20 0.56
TNKS O95271 1/20 0.56
TNKS2 Q9H2K2 1/20 0.56
KDM4E B2RXH2 2/20 0.53
ATM Q13315 2/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
AKR1C4 P17516 1/20 0.51
AKR1C3 P42330 1/20 0.51
AKR1C2 P52895 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2945957 0.83 KDM4E (0.65) HDAC4KDM4EATML3MBTL1PKM
SCHEMBL2945952 0.83 KDM4E (0.65) HDAC4KDM4EATML3MBTL1PKM
SCHEMBL28506734 0.83 PLA2G4A (0.59) HDAC4HDAC6HDAC3HDAC1HDAC2
SCHEMBL13988760 0.82 KDM4E (0.64) HDAC4KDM4EATML3MBTL1SMN1; SMN2
SCHEMBL14982726 0.82 KDM4E (0.64) HDAC4KDM4EATML3MBTL1SMN1; SMN2
SCHEMBL31084773 0.82 KDM4E (0.64) HDAC4KDM4EATML3MBTL1SMN1; SMN2
SCHEMBL13142004 0.82 KDM4E (0.64) HDAC4KDM4EATML3MBTL1SMN1; SMN2
SCHEMBL16756631 0.82 KDM4E (0.64) HDAC4KDM4EATML3MBTL1SMN1; SMN2
SCHEMBL29441870 0.82 KDM4E (0.64) HDAC4KDM4EATML3MBTL1SMN1; SMN2
SCHEMBL14466726 0.79 KDM4E (0.59) HDAC4HDAC6HDAC3HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230314934-A1 PHOTOACTIVE COMPOUNDS, PHOTORESIST COMPOSITIONS INCLUDING THE SAME, AND PATTERN FORMATION METHODS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2023-10-05 US disclosed
US-20230314934-A1 PHOTOACTIVE COMPOUNDS, PHOTORESIST COMPOSITIONS INCLUDING THE SAME, AND PATTERN FORMATION METHODS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2023-10-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230314934-A1 PHOTOACTIVE COMPOUNDS, PHOTORESIST COMPOSITIONS INCLUDING THE SAME, AND PATTERN FORMATION METHODS CRY1, CBR3, C1S HDAC4 4213/4885HDAC6 4283/4885HDAC3 2264/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.