SCHEMBL26080880

SCHEMBL26080880

N#CC1=C(C(=O)O)CCc2ccccc21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 2/20 0.46
SRD5A1 P18405 1/20 0.46
NOTUM Q6P988 3/20 0.43
KDM4E B2RXH2 3/20 0.43
ALDH1A1 P00352 3/20 0.43
LMNA P02545 2/20 0.43
HPGD P15428 1/20 0.43
CES1 P23141 1/20 0.41
RAB9A P51151 2/20 0.39
NPC1 O15118 1/20 0.39
CYP2A6 P11509 1/20 0.38
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
MAPT P10636 2/20 0.38
GSR P00390 1/20 0.38
MITF O75030 1/20 0.37
HSP90AA1 P07900 1/20 0.37
MAPK1 P28482 1/20 0.36
PTAFR P25105 1/20 0.36
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24282949 0.75 ALDH1A1 (0.51) SRD5A2SRD5A1NOTUMKDM4EALDH1A1
SCHEMBL9617185 0.75 SRD5A2 (0.51) SRD5A2SRD5A1NOTUMKDM4EALDH1A1
SCHEMBL15111695 0.74 SRD5A2 (0.50) SRD5A2SRD5A1NOTUMKDM4EALDH1A1
SCHEMBL947675 0.74 SRD5A1 (0.50) SRD5A2SRD5A1NOTUMKDM4EALDH1A1
SCHEMBL2063312 0.72 CES1 (0.42) SRD5A2SRD5A1KDM4EALDH1A1LMNA
SCHEMBL9720856 0.72 CES1 (0.42) SRD5A2SRD5A1KDM4EALDH1A1LMNA
SCHEMBL28533163 0.71 MAOB (0.61) SRD5A2SRD5A1CES1CYP2A6MAOA
SCHEMBL28728806 0.70 KDM4E (0.46) SRD5A2SRD5A1NOTUMKDM4EALDH1A1
SCHEMBL9580724 0.70 SRD5A2 (0.46) SRD5A2SRD5A1NOTUMKDM4EALDH1A1
SCHEMBL314649 0.70 CES1 (0.42) SRD5A2SRD5A1KDM4EALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230314934-A1 PHOTOACTIVE COMPOUNDS, PHOTORESIST COMPOSITIONS INCLUDING THE SAME, AND PATTERN FORMATION METHODS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2023-10-05 US disclosed
US-20230314934-A1 PHOTOACTIVE COMPOUNDS, PHOTORESIST COMPOSITIONS INCLUDING THE SAME, AND PATTERN FORMATION METHODS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2023-10-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230314934-A1 PHOTOACTIVE COMPOUNDS, PHOTORESIST COMPOSITIONS INCLUDING THE SAME, AND PATTERN FORMATION METHODS CRY1, CBR3, C1S SRD5A2 2268/4885SRD5A1 2131/4885NOTUM 2012/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.