SCHEMBL26080997

SCHEMBL26080997

C=Cc1ccc(C(=O)OCC(C)(F)F)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 5/20 0.44
ADRB1 P08588 5/20 0.44
ADRB3 P13945 5/20 0.44
ALDH1A1 P00352 2/20 0.42
KMT2A Q03164 1/20 0.42
SNCA P37840 1/20 0.41
MAPK1 P28482 2/20 0.41
HIF1A Q16665 1/20 0.41
TAS1R3 Q7RTX0 2/20 0.41
TAS1R1 Q7RTX1 2/20 0.41
PDK1 Q15118 1/20 0.39
PDK2 Q15119 1/20 0.39
PDK3 Q15120 1/20 0.39
PDK4 Q16654 1/20 0.39
HTR1A P08908 1/20 0.38
CYP2D6 P10635 1/20 0.38
SCN1A P35498 1/20 0.38
SLC6A3 Q01959 1/20 0.38
SCN5A Q14524 1/20 0.38
SCN2A Q99250 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4378876 0.87 MAPK1 (0.43) ADRB2ADRB1ADRB3ALDH1A1KMT2A
SCHEMBL14330820 0.81 MAPK1 (0.43) ADRB2ADRB1ADRB3ALDH1A1KMT2A
SCHEMBL10134911 0.81 TDP1 (0.40) ADRB2ADRB1ADRB3ALDH1A1KMT2A
SCHEMBL24305987 0.80 MAPK1 (0.60) ADRB2ADRB1ADRB3ALDH1A1KMT2A
SCHEMBL26080998 0.80 SNCA (0.41) ADRB2ADRB1ADRB3ALDH1A1SNCA
SCHEMBL17628392 0.80 SNCA (0.38) ADRB2ADRB1ADRB3ALDH1A1KMT2A
SCHEMBL1052411 0.78 CA1 (0.61) ALDH1A1KMT2ATAS1R3TAS1R1TDP1
SCHEMBL8258980 0.78 MAPK1 (0.67) ADRB2ADRB1ADRB3ALDH1A1KMT2A
SCHEMBL26417020 0.78 SNCA (0.49) ALDH1A1KMT2ASNCAMAPK1TAS1R3
SCHEMBL26810445 0.78 SNCA (0.49) ADRB2ADRB1ADRB3ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240241441-A1 POLYMER, PHOTORESIST COMPOSITIONS INCLUDING THE SAME, AND PATTERN FORMATION METHODS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2024-07-18 US disclosed
US-20240241440-A1 POLYMER, PHOTORESIST COMPOSITIONS INCLUDING THE SAME, AND PATTERN FORMATION METHODS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2024-07-18 US disclosed
US-20240019779-A1 COMPOUNDS AND PHOTORESIST COMPOSITIONS INCLUDING THE SAME U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2024-01-18 US disclosed
US-20230314934-A1 PHOTOACTIVE COMPOUNDS, PHOTORESIST COMPOSITIONS INCLUDING THE SAME, AND PATTERN FORMATION METHODS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2023-10-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240019779-A1 COMPOUNDS AND PHOTORESIST COMPOSITIONS INCLUDING THE SAME CRY1, CCNT1, CCNA1 ADRB2 956/4885ADRB1 454/4885ADRB3 1669/4885
US-20230314934-A1 PHOTOACTIVE COMPOUNDS, PHOTORESIST COMPOSITIONS INCLUDING THE SAME, AND PATTERN FORMATION METHODS CRY1, CBR3, C1S ADRB2 2096/4885ADRB1 2113/4885ADRB3 1467/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.