Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26080997 | 0.87 | ADRB2 (0.44) | MAPK1HIF1ASNCATAS1R3TAS1R1 | |
| SCHEMBL1496824 | 0.86 | MAPK1 (0.55) | MAPK1HIF1AHTTJMJD6ALDH1A1 | |
| SCHEMBL5794633 | 0.85 | ALDH1A1 (0.53) | MAPK1HIF1ASNCAHTTADRB2 | |
| SCHEMBL10134911 | 0.83 | TDP1 (0.40) | MAPK1HIF1ASNCATAS1R3TAS1R1 | |
| SCHEMBL29030403 | 0.82 | SNCA (0.47) | SNCATAS1R3TAS1R1ADRB2ADRB1 | |
| SCHEMBL17628392 | 0.82 | SNCA (0.38) | MAPK1HIF1ASNCATAS1R3TAS1R1 | |
| SCHEMBL26810445 | 0.80 | SNCA (0.49) | MAPK1HIF1ASNCATAS1R3TAS1R1 | |
| SCHEMBL26417020 | 0.80 | SNCA (0.49) | MAPK1SNCATAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL9244575 | 0.79 | ADRB2 (0.49) | MAPK1HIF1AHTTADRB2ADRB1 | |
| SCHEMBL7945129 | 0.79 | ESR1 (0.58) | MAPK1HIF1AADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090298139-A1 | Method for Polymer Synthesis Using Microfluidic Enzymatic Cascade | AIR FORCE, UNITED STATES | 2009-12-03 | — | — | US | disclosed |
| WO-2007100831-A2 | METHOD FOR POLYMER SYNTHESIS USING MICROFLUIDIC ENZYMATIC CASCADE | TUFTS UNIVERSITY (US) | 2007-09-07 | — | — | WO | disclosed |
| US-20070010632-A1 | Antioxidant-functionalized polymers | TRUSTEES OF TUFTS COLLEGE | 2007-01-11 | — | — | US | disclosed |
| US-20070010632-A1 | Antioxidant-functionalized polymers | TRUSTEES OF TUFTS COLLEGE | 2007-01-11 | — | — | US | disclosed |
| WO-2004050795-A2 | ANTIOXIDANT-FUNCTIONALIZED POLYMERS | TUFTS UNIVERSITY (US) | 2004-06-17 | — | — | WO | disclosed |