SCHEMBL26081709

CC(=O)N[C@H]1[C@H](OCCCCNC(=O)CCCC(=O)NCCCCC(NC(=O)[C@H](CCCCN[C@@H](O)CCC[C@@H](O)NCCCCO[C@@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2NC(C)=O)NC(=O)C(CCCCNC(=O)CCCC(=O)NCCCCO[C@@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2NC(C)=O)NC(=O)COCCOCCNC(=O)COCCOCCNC(=O)CCCCCNC(=O)CCCCC2SC[C@@H]3NC(=O)N[C@H]23)C(N)=O)O[C@H](CO)[C@H](O)[C@@H]1O

nearest known ligand 0.54

Predicted protein targets (top 20)

	gene	UniProt	supporting neighbours	confidence
▸	MDK	P21741	4/20	0.54

▸	FOLH1	Q04609	7/20	0.46

▸	FGF1	P05230	1/20	0.45

▸	FGF2	P09038	1/20	0.45

▸	VEGFA	P15692	1/20	0.45

▸	HPSE	Q9Y251	1/20	0.45

▸	PRSS1	P07477	2/20	0.42

▸	PRSS2	P07478	2/20	0.42

▸	PRSS3	P35030	2/20	0.42

▸	TPSAB1	Q15661	2/20	0.42

▸	F2	P00734	1/20	0.42

▸	PTPN2	P17706	1/20	0.41

▸	PTPN1	P18031	1/20	0.41

▸	PLG	P00747	1/20	0.41

▸	PKM	P14618	2/20	0.41

▸	TDP1	Q9NUW8	1/20	0.41

▸	ESR1	P03372	1/20	0.41

▸	PGR	P06401	1/20	0.41

▸	HTR1A	P08908	1/20	0.41

▸	ADORA3	P0DMS8	1/20	0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL14500481	0.86	MDK (0.52)	MDKFOLH1FGF1FGF2VEGFA
SCHEMBL8120683	0.86	MDK (0.53)	MDKFOLH1FGF1FGF2VEGFA
SCHEMBL12743545	0.85	MDK (0.53)	MDKFOLH1FGF1FGF2VEGFA
SCHEMBL12767779	0.83	MDK (0.50)	MDKFOLH1FGF1FGF2VEGFA
SCHEMBL17359466	0.81	ESR1 (0.56)	ESR1PGRHTR1AADORA3AR
SCHEMBL18653674	0.81	MDK (0.75)	MDKFOLH1FGF1FGF2VEGFA
SCHEMBL16264872	0.81	MDK (0.75)	MDKFOLH1FGF1FGF2VEGFA
SCHEMBL12147669	0.79	MDK (0.50)	MDKFOLH1FGF1FGF2VEGFA
SCHEMBL16920715	0.79	ESR1 (0.47)	ESR1PGRHTR1AADORA3AR
SCHEMBL16408402	0.77	FOLH1 (0.58)	FOLH1PRSS1PRSS2PRSS3TPSAB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20230314417-A1	MONOCLONAL ANTIBODIES TO CHEMICALLY-MODIFIED NUCLEIC ACIDS AND USES THEREOF	AMGEN INC. (US)	2023-10-05	—	—	US	disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

Patent	Title	Text reads most about	Predicted target · text-rank
US-20230314417-A1	MONOCLONAL ANTIBODIES TO CHEMICALLY-MODIFIED NUCLEIC ACIDS AND USES THEREOF	NT5C3B, NSUN3, POLI	MDK 2165/4885FOLH1 1169/4885FGF1 3614/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.