Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26082660 | 0.81 | CACNA1I (0.60) | ALDH1A1MEN1KMT2AACKR3 | |
| SCHEMBL23839974 | 0.78 | CAPN1 (0.63) | ACKR3THRB | |
| SCHEMBL8083501 | 0.77 | ERCC1 (0.65) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL26082659 | 0.76 | CACNA1I (0.61) | ALDH1A1KMT2AACKR3POLB | |
| SCHEMBL26082619 | 0.74 | EPHX2 (0.56) | GAAHTTALDH1A1MEN1KMT2A | |
| SCHEMBL13203840 | 0.73 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL10113306 | 0.73 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL19808535 | 0.73 | IDO1 (0.52) | SMN1; SMN2ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL26082621 | 0.73 | ACKR3 (0.43) | LMNASMN1; SMN2GAAHTTALDH1A1 | |
| SCHEMBL13003526 | 0.72 | ALDH1A1 (0.53) | LMNAALDH1A1ACKR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192687-A1 | T-TYPE CALCIUM CHANNEL MODULATORS COMPRISING AN AZASPIROHEPTANE CORE AND METHODS OF USE THEREOF | PRAXIS PRECISION MEDICINES, INC. (US) | 2023-10-05 | — | — | WO | disclosed |