Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 1/20 | 0.65 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | METAP2 | P50579 | 1/20 | 0.55 |
| ▸ | METAP1 | P53582 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | SMO | Q99835 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8097845 | 0.86 | MTNR1A (0.56) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL31176222 | 0.83 | MTNR1A (0.56) | ALDH1A1HPGDUSP2MEN1KMT2A | |
| SCHEMBL9131926 | 0.83 | MTNR1A (0.56) | ALDH1A1HPGDUSP2MEN1KMT2A | |
| SCHEMBL6244724 | 0.81 | ALDH1A1 (0.93) | ERCC1ERCC4ALDH1A1HPGDUSP2 | |
| SCHEMBL507837 | 0.80 | ALDH1A1 (0.90) | ERCC1ERCC4ALDH1A1HPGDUSP2 | |
| SCHEMBL9130436 | 0.79 | MTNR1A (0.54) | MEN1KMT2A | |
| SCHEMBL23839974 | 0.79 | CAPN1 (0.63) | — | |
| SCHEMBL13203840 | 0.79 | ALDH1A1 (0.47) | ERCC1ERCC4ALDH1A1HPGDUSP2 | |
| SCHEMBL10113306 | 0.79 | ALDH1A1 (0.47) | ERCC1ERCC4ALDH1A1HPGDUSP2 | |
| SCHEMBL10114093 | 0.78 | ALDH1A1 (0.47) | ERCC1ERCC4ALDH1A1HPGDUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | disclosed |