SCHEMBL2608360

SCHEMBL2608360

C=CC(=O)OCCOC(=O)c1cc(C=O)ccc1O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.42
SERPINE1 P05121 1/20 0.42
ALDH1A1 P00352 6/20 0.41
TSHR P16473 5/20 0.41
TP53 P04637 3/20 0.41
HIF1A Q16665 3/20 0.41
PTGS2 P35354 3/20 0.41
HSD17B10 Q99714 3/20 0.41
KDM4E B2RXH2 2/20 0.41
RAB9A P51151 1/20 0.41
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40
CA14 Q9ULX7 1/20 0.40
APP P05067 4/20 0.39
TDP1 Q9NUW8 3/20 0.39
HPGD P15428 2/20 0.39
TRIM24 O15164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20110399 0.84 CA12 (0.58) THRBSERPINE1ALDH1A1TSHRTP53
SCHEMBL2608361 0.82 SERPINE1 (0.43) THRBSERPINE1ALDH1A1TSHRTP53
SCHEMBL20346761 0.81 CYP3A4 (0.54) ALDH1A1TSHRPTGS2HSD17B10KDM4E
SCHEMBL2612584 0.81 L3MBTL1 (0.53) SERPINE1ALDH1A1TSHRPTGS2KDM4E
SCHEMBL2608353 0.80 L3MBTL1 (0.46) SERPINE1ALDH1A1TSHRPTGS2KDM4E
SCHEMBL15425253 0.79 CA12 (0.55) SERPINE1ALDH1A1TSHRPTGS2CA12
SCHEMBL2608364 0.79 TSHR (0.54) ALDH1A1TSHRTP53HSD17B10CA12
SCHEMBL961565 0.78 TDP1 (0.65) THRBSERPINE1ALDH1A1TSHRTP53
SCHEMBL5272506 0.78 ALDH1A1 (0.50) THRBALDH1A1TSHRTP53HIF1A
SCHEMBL4755004 0.78 CA12 (0.66) ALDH1A1TSHRPTGS2KDM4ERAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8158021-B2 Polymerizable liquid crystal compound, polymerizable liquid crystal composition, liquid crystalline polymer, and optical anisotropic article ZEON CORPORATION (JP) 2012-04-17 US disclosed
US-20100258764-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTALLINE POLYMER, AND OPTICAL ANISOTROPIC ARTICLE ZEON CORPORATION (JP) 2010-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100258764-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTALLINE POLYMER, AND OPTICAL ANISOTROPIC ARTICLE LEO1, ZYX, CCNT1 THRB 4283/4885SERPINE1 2285/4885ALDH1A1 2720/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.