Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.52 |
| ▸ | CA2 | P00918 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | GBA1 | P04062 | 2/20 | 0.43 |
| ▸ | SDCBP | O00560 | 1/20 | 0.40 |
| ▸ | SDC2 | P34741 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.38 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | BRD2 | P25440 | 1/20 | 0.38 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18237012 | 0.99 | CA1 (0.51) | CA1CA2CYP3A4GBA1SDCBP | |
| SCHEMBL29383217 | 0.99 | CA1 (0.51) | CA1CA2CYP3A4GBA1SDCBP | |
| SCHEMBL15748075 | 0.86 | SMN1; SMN2 (0.41) | HDAC1LMNATPSAB1 | |
| SCHEMBL15748539 | 0.86 | TPSAB1 (0.42) | HDAC1LMNASUCNR1TPSAB1 | |
| SCHEMBL26085368 | 0.85 | TPSAB1 (0.47) | CA1CA2CYP3A4HDAC1LMNA | |
| SCHEMBL18222840 | 0.85 | GAA (0.43) | HDAC1LMNASUCNR1TPSAB1 | |
| SCHEMBL18237011 | 0.84 | TPSAB1 (0.46) | CA1CA2CYP3A4HDAC1LMNA | |
| SCHEMBL29386153 | 0.84 | TPSAB1 (0.46) | CA1CA2CYP3A4HDAC1LMNA | |
| SCHEMBL16616006 | 0.83 | NAMPT (0.53) | CA1CA2SDCBPSDC2NAMPT | |
| SCHEMBL18222828 | 0.82 | MEN1 (0.36) | CA1CA2HDAC1LMNATPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230310643-A1 | EXTRACORPOREAL CLEARING TRAPS BASED ON INVERSE ELECTRON DEMAND DIELS-ALDER CYCLOADDITION FOR (PRE)-TARGETED THERAPY AND DIAGNOSTICS | RIGSHOSPITALET (DK) | 2023-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230310643-A1 | EXTRACORPOREAL CLEARING TRAPS BASED ON INVERSE ELECTRON DEMAND DIELS-ALDER CYCLOADDITION FOR (PRE)-TARGETED THERAPY AND DIAGNOSTICS | ECE1, ELANE, EDNRA | CA1 3300/4885CA2 4166/4885CYP3A4 2530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.